We isolated mutations in Arabidopsis to understand how the female gametophyte controls embryo and endosperm development. For the DEMETER (DME) gene, seed viability depends only on the maternal allele. DME encodes a large protein with DNA glycosylase and nuclear localization domains. DME is expressed primarily in the central cell of the female gametophyte, the progenitor of the endosperm. DME is...

Calcium and strontium metals react with Hg(C6F5)2 and 2,4-di-tert-butylphenol (H-DBP) in tetrahydrofuran (THF) and 1,2-dimethoxyethane (DME) to give [Ca(DBP)2(THF)4] (1), [Ca2(DBP)4(DME)4(μ-DME)] (2), [Sr3(μ-DBP)6(THF)6] (3), and [Sr2(DBP)(μ-DBP)3(DME)3] (4). Compound 1 is a six coordinate trans-octahedral monomer, whereas in binuclear 2 two seven-coordinate Ca centres are bridged by a DME liga...

Diabetic macular edema (DME) is the main cause of visual impairment in diabetic patients. The management of DME is complex and often various treatment approaches are needed. At the present time, despite the enthusiasm for evaluating several new treatments for DME, including the intravitreal pharmacologic therapies (e.g., corticosteroids and anti-VEGF drugs), laser photocoagulation still remains...

This paper presents new single-layer, i.e., planar-embeddable, clock tree constructions with exact zero skew under either the linear or the Elmore delay model. Our method, called Planar-DME, consists of two parts. The rst algorithm, called Linear-Planar-DME, guarantees an optimal planar zero-skew clock tree (ZST) under the linear delay model. The second algorithm, called ElmorePlanar-DME, uses ...

The effects of dimethyl ether (DME) addition on the high temperature ignition and burning properties of methane–air mixtures were studied experimentally and numerically. The results showed that for a homogeneous system, a small amount of DME addition to methane resulted in a significant reduction in the high temperature ignition delay. The ignition enhancement effect by DME addition was found t...

AIMS To study the association between peripheral blood metabolic and inflammatory factors and presence of diabetic macular edema (DME) and its related anatomic features in type 2 diabetic mellitus (T2DM) patients. MATERIAL AND METHODS Observational cross-sectional study on a proof of concept basis. Seventy-six T2DM included patients were divided based on the presence (n = 58) or absence of DM...

IMPORTANCE Thickening of the center of the retina, diabetic macular edema (DME), is the most common cause of visual loss due to diabetes mellitus. Treatment of DME has improved dramatically, and the prompt diagnosis of DME and referral of these patients have become more critical. Nonetheless, awareness of and care for DME in the US population is uncharacterized. OBJECTIVE To characterize eye ...

In double fertilization, the vegetative cell of the male gametophyte (pollen) germinates and forms a pollen tube that brings to the female gametophyte two sperm cells that fertilize the egg and central cell to form the embryo and endosperm, respectively. The 5-methylcytosine DNA glycosylase DEMETER (DME), expressed in the central cell, is required for maternal allele demethylation and gene impr...

The effects of dimethyl ether (DME) addition on the high temperature ignition and burning properties of methane-air mixtures were studied experimentally and numerically. The results showed that for a homogeneous system, a small amount of DME addition to methane resulted in a significant reduction in the high temperature ignition delay. The ignition enhancement effect by DME addition was found t...

diabetic macular edema (dme) is a leading cause of vision loss in the working-age population worldwide. numerous early studies suggest an important role for intravitreal anti-vegf agents such as bevacizumab in the management of dme. we reviewed manuscripts that had investigated pharmacokinetic, efficacy, safety, dose and frequency of intravitreal bevacizumab (ivb) injections as well as effect o...