نتایج جستجو برای: dka

تعداد نتایج: 774  

Journal: :Diabetes research and clinical practice 2017
M Varadarajan M Patel N Kakkar E Li Ping Wah-Pun Sin D Maxey I Nunney K Dhatariya

BACKGROUND In 2013 the Joint British Diabetes Societies published an update to their 2010 guideline on the management of diabetic ketoacidosis (DKA). In 2014 a national survey was conducted to assess the management of DKA across the UK using the JBDS or local guidelines. Hospitals were invited to submit data on 5 people presenting with DKA. These data were published in 2016. However, whether th...

Journal: :Diabetes 2005
Tina I Lam Steven E Anderson Nicole Glaser Martha E O'Donnell

The mechanisms responsible for cerebral edema formation in diabetic ketoacidosis (DKA) are not well understood, although evidence suggests ischemia as a contributing factor. Previous studies have shown that the Na-K-Cl cotransporter of cerebral microvascular endothelial cells and astrocytes is a major participant in ischemia-induced cerebral edema in stroke. The present study was conducted to t...

2015
Ngozi Erondu Mehul Desai Kirk Ways Gary Meininger

OBJECTIVE This study assessed the incidence of serious adverse events of diabetic ketoacidosis (DKA) among patients with type 2 diabetes treated with canagliflozin. RESEARCH DESIGN AND METHODS All serious adverse events of DKA and related events (ketoacidosis, metabolic acidosis, and acidosis) from 17,596 patients from randomized studies of canagliflozin through 11 May 2015 were analyzed. R...

Journal: :AJNR. American journal of neuroradiology 2005
Sandra L Wootton-Gorges Michael H Buonocore Nathan Kuppermann James Marcin Joseph Dicarlo E Kirk Neely Patrick D Barnes Nicole Glaser

BACKGROUND AND PURPOSE Ketone bodies provide important alternate fuel for brain metabolism, and their transport into the brain increases with prolonged fasting. During diabetic ketoacidosis (DKA), serum ketone concentrations markedly increase; however, little is known about whether ketone bodies accumulate in cerebral tissues during DKA. We used proton MR spectroscopy (MRS) to detect cerebral b...

2008
Baligh Ramzi Yehia

Hospital Physician March 2008 21 D iabetic ketoacidosis (DKA) is a serious and potentially life-threatening complication of diabetes mellitus.1,2 It represents a state of insulin deficiency with a concurrent elevation in counterregulatory hormones.2–6 The annual incidence ranges from 4.6 to 8 cases per 1000 diabetic patients, and DKA carries a mortality rate of 2% to 10%.2 DKA occurs more commo...

2017
Hye Jin Lee Hyeoh Won Yu Hae Woon Jung Young Ah Lee Jae Hyun Kim Hye Rim Chung Jaeho Yoo Eunyoung Kim Jeesuk Yu Choong Ho Shin Sei Won Yang Seong Yong Lee

The aim of this study was to identify the risk factors for presence and severity of diabetic ketoacidosis (DKA) at the onset of type 1 diabetes mellitus (T1DM) in Korean children and adolescents. A retrospective chart review of children and adolescents newly diagnosed with T1DM was conducted in seven secondary and tertiary centers in Korea. Eligible subjects were < 20 years of age and had recor...

2017
Tara T. T. Tran Anthony Pease Anna J. Wood Jeffrey D. Zajac Johan Mårtensson Rinaldo Bellomo Elif I. I. Ekinci

BACKGROUND Diabetic ketoacidosis (DKA) is an endocrine emergency with associated risk of morbidity and mortality. Despite this, DKA management lacks strong evidence due to the absence of large randomised controlled trials (RCTs). OBJECTIVE To review existing studies investigating inpatient DKA management in adults, focusing on intravenous (IV) fluids; insulin administration; potassium, bicarb...

2014
Viktor Rosival Aidar R Gosmanov Elvira O Gosmanova

Diabetic ketoacidosis (DKA) is a rare yet potentially fatal hyperglycemic crisis that can occur in patients with both type 1 and 2 diabetes mellitus. Due to its increasing incidence and economic impact related to the treatment and associated morbidity, effective management and prevention is key. Elements of management include making the appropriate diagnosis using current laboratory tools and c...

2013
Vishal Sehgal Sukhminder jit Singh Bajwa Abbas Kitabchi

Non-Insulin Dependent Diabetes Mellitus (NIDDM) is a common disease entity in patients with Coronary Artery Disease (CAD). Diabetic Ketoacidosis (DKA) is not only one of the major complications of Diabetes Mellitus but also a significant challenging clinical entity for the patients undergoing any elective or emergency surgery. Coronary Artery Bypass Grafting (CABG) being done in a patient with ...

2016
Joanne Brooke Marlon Stiell Omorogieva Ojo

A complication of diabetes is diabetic ketoacidosis (DKA), which if left untreated is a life threatening condition. Prompt and accurate diagnosis of DKA is required for the commencement of life saving interventions. Measurements of ketone bodies in DKA have usually been through nitroprusside urine acetoacetate testing. The aim of this systematic review was to examine whether capillary β-hydroxy...

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