HIV-1 genomic RNA has a noncoding 5' region containing sequential conserved structural motifs that control many parts of the life cycle. Very limited data exist on their three-dimensional (3D) conformation and, hence, how they work structurally. To assemble a working model, we experimentally reassessed secondary structure elements of a 240-nt region and used single-molecule distances, derived f...

Abstract We exhibit a class of integer spin systems whose free energy can be written in term of an absolutely convergent series at any temperature. This class includes spin systems on Z interacting through infinite range pair potential polynomially decaying at large distances r at a rate 1/r with ε > 0. It also contains the Blume-Emery-Griffiths model in the disordered phase at large values of ...

Scenario reduction techniques are widely applied for solving sophisticated dynamic and stochastic programs, especially in energy power systems, but also used probabilistic forecasting, clustering estimating generative adversarial networks. We propose a new method ensemble scenario based on the distance which is special case of maximum mean discrepancy. discuss choice detail, comparison to popul...