A new rK39 rapid diagnostic dipstick test (DiaMed-IT-Leish) was compared with aspiration and a direct agglutination test (DAT) for diagnosis of visceral leishmaniasis (VL) in 201 parasitologically confirmed cases, 133 endemic controls, and in 356 clinical suspects in disease-endemic and -epidemic areas in Sudan. The sensitivity of the rK39 test in parasitologically confirmed VL cases was 90%, w...

Visual object recognition and naming deficits in patients with dementia of the Alzheimer type (DAT) have typically been attributed to deficits in semantic processing. On a visual object naming test, a group of 10 mild, early stage DAT patients (mean MMSE=23.8) were found to suffer from anomia, compared to a group of 10 age-matched control participants. DAT naming errors were typically within ca...

The objectives of this study were to compare the sensitivities and reliabilities of direct agglutination test (DAT), indirect immunofluorescent antibody test (IFAT), polymerase chain reaction (PCR) and bone marrow aspiration for the diagnosis of Mediterranean visceral leishmaniasis (MVL) using blood samples. Blood samples were collected from 67 confirmed MVL patients and 47 patients with other ...

We assayed blood/tissue fluid samples from 20 harbour porpoises Phocoena phocoena from western Greenland coastal waters for antibodies against the protozoan parasite Toxoplasma gondii by the direct agglutination test (DAT). Nine individuals (45%) were interpreted to be seropositive at 1:40 dilution and 4 (20%) were seropositive up to 1:160. Samples from these individuals were assayed by an enzy...

BACKGROUND AND OBJECTIVES We recently demonstrated that direct antiglobulin titer (DAT) positive, blood group A or B newborns born to group O mothers had a high incidence of hyperbilirubinemia, attributable to increased hemolysis. We reanalyzed our data asking whether increasing DAT strength plays a modulating role in the pathophysiology of the hemolysis and hyperbilirubinemia. METHODS Data f...

background: visceral leishmaniasis (vl) is an endemic disease in some parts of iran. many techniques have been used for diagnosis of vl, among which the urine based la-tex agglutination test (katex) is a promising one. objective: to compare three diag-nostic tests of vl including katex, elisa and direct agglutination test (dat) in vl patients and healthy controls in the south west of iran. meth...

Cocaine blocks the normal role of the dopamine transporter (DAT) in terminating dopamine signaling through molecular interactions that are only partially understood. Cocaine analog structure-activity studies have suggested roles for both cationic and aromatic interactions among DAT, dopamine, and cocaine. We hypothesized that phenylalanine residues lying in putative DAT transmembrane (TM) domai...

Background: Parkinson’s disease (PD) is a complex disorder that involves multiple genetic and environmental factors. Several candidate genes have been speculated to be involved in the development of PD. We conducted a case-control study to investigate the association between PD and single nucleotide polymorphisms (SNP) at the OPRM1, DAT, COMT and DRD2 genes in a Taiwanese population. Methods: T...