The asymmetric unit of the title compound, C(22)H(16)N(6)O(6)S(2)·2C(2)H(6)OS, consists of one half-mol-ecule of the centrosymmetric thiourea derivative and one molecule of dimethyl sulfoxide (DMSO). The carbonyl group forms an intra-molecular hydrogen bond with the NH group, creating a six-membered (C-N-C-N-H⋯O) ring. Two other N-H⋯O hydro-gen bonds link one mol-ecule of the thio-urea to two m...

Kaliocin-1, a 31-residue synthetic peptide (FFSASCVPGADKGQFPNLCRLCA GTGENKCA), which has shown the antimicrobial activity forms the 152-182 fragment of human lactoferrin (HLf). As the octapeptide FSASCVPG forms the 2-9 fragment of kaliocin-1, in the present study, its conformation in dimethyl sulfoxide-d6 (DMSO-d6) has been determined using two-dimensional (2D) nuclear magnetic resonance (NMR) ...

All cellulose composites (ACCs) were produced by partially dissolving alternating layers of cotton textile and film in solvent solution heating them under an applied pressure. The ionic liquid 1-ethyl-3-methylimidazolium acetate ([C2MIM][OAc]) combined with a co-solvent dimethyl sulfoxide (DMSO) was used this work, iterative approach employed to identify the combination [C2MIM][OAc] DMSO yield ...

In this paper we report classical Molecular Dynamics and ab initio Density Functional Theory simulations of the structure single particle dynamics ternary mixtures a protic (ethylammonium nitrate, EAN) an aprotic (1-Ethyl-3-methylimidazolium tetrafluoroborate, EMIMBF4) ionic liquid, lithium salts with common anion molecular cosolvent, dimethyl sulfoxide (DMSO). The coordination numbers electric...

Effect of different solvents; dimethyl-sulfoxide (DMSO), dimethyl formamide (DMF), methanol, tween 80 and acetone on morphology, cytology and reproduction of Aspergillus flavus, A. parasiticus, A. fumigatus and A. niger was assayed for standardization of a suitable organic solvent for test/antimicrobial compound in antimicrobial assays. Comparison of antimicrobial sensitivity methods was also m...

Cryoprotectants have critical roles to prevent cell damages during cryopreservation. However, the adjustment of cryoprotectant concentration is also very crucial protect cells from toxicity. The present study was designed investigate effect extenders including high dimethyl sulfoxide (DMSO) on post-thaw rabbit sperm quality. Pooled samples (n=7) were diluted and cryopreserved in 250 mmol/L Tris...

An alteration in the rate of calcium transport appears to be the rate-limiting event for the commitment of murine erythroleukemia (MEL) cells to initiate a program of terminal erythroid differentiation. The dimethyl sulfoxide (DMSO)-induced commitment of MEL cells to erythroid differentiation can be inhibited by treatment of cells with the calcium-chelating agent EGTA. Upon removal of EGTA, cel...

The enormous molecular weight complicates detailed structural studies of amyloid fibrils and obscures identification of biologically active forms of protein aggregates in amyloid-related diseases. Here we show that aqueous solutions of dimethyl sulfoxide (DMSO) solubilize insulin fibrils while maintaining their beta-pleated structure. This is accompanied by a marked decrease in the fluorescence...

Dimethyl sulfoxide (DMSO) is a well-known hydroxyl radical scavenger, which is readily absorbed through biological membranes. We studied the effects of locally applied DMSO on acute spinal cord injury. Either 10% DMSO in saline (n=8) or saline alone (n=7) was applied directly to the exposed cervical spinal cord of rats 1 hour after clip compression injury of 26 g force for 1 minute. The outcome...