We studied 40 patients with stroke of potential cardioembolic origin by cardiac ultrafast computed tomography and two-dimensional echocardiography. Cardiac ultrafast computed tomography was more sensitive (positive in eight of 14 instances) than two-dimensional echocardiography (positive in two of 14 instances) for the detection of intracardiac thrombus, which was found in 13 patients. Mitral a...

SEE PAGE 804 T he procedural success rates of percutaneous intervention for chronic total coronary occlusions (CTOs) over the past decade have been increasing, driven by the development of specialized guidewires and microcatheters and the introduction of new technical strategies, including antegrade subintimal re-entry and the retrograde transcollateral approach. An ongoing challenge is to sele...

We developed SPECT imaging capability on an animal PET scanner to provide a cost effective option for animal SPECT imaging. The SPECT add-on sub-system was enabled by mechanically integrating a multiple-pinhole collimator in the PET detector ring. This study introduces a method to calibrate the geometrical parameters of the SPECT add-on using the PET imaging capability of the scanner. The propo...

Review of our records for a 2-year period (1985-1986) yielded 15 patients in whom unequivocally normal myelograms and postmetrizamide CT scans had been obtained before diskography. In none of these patients was the diskogram or postdiskography CT scan positive for either central, posterolateral, or extreme lateral disk herniation. It was our experience that, with the new-generation, improved-re...

Beamline 2.1 (XM-2) is a transmission soft X-ray microscope in sector 2 of the Advanced Light Source at Lawrence Berkeley National Laboratory. XM-2 was designed, built and is now operated by the National Center for X-ray Tomography as a National Institutes of Health Biomedical Technology Research Resource. XM-2 is equipped with a cryogenic rotation stage to enable tomographic data collection fr...

Using medical evidence to effectively guide medical practice is an important skill for all physicians to learn. The purpose of this article is to understand how to ask and evaluate questions of diagnosis, and then apply this knowledge to the new diagnostic test of CT colonography to demonstrate its applicability. Sackett and colleagues have developed a step-wise approach to answering questions ...

OBJECTIVE The purpose of this article is to detail an approach to CT colonographic screening that has evolved at one institution. CONCLUSION CT colonography is a rapidly advancing technology that has great potential for addressing a deadly but preventable disease-colorectal carcinoma. CT colonography is ideally suited for widespread screening of asymptomatic adults and has become an integral ...

Echocardiography is one of the most important diagnostic tools in veterinary cardiology, and one of the greatest recent developments is real-time three-dimensional imaging. Real-time three-dimensional echocardiography is a new ultrasonography modality that provides comprehensive views of the cardiac valves and congenital heart defects. The main advantages of this technique, particularly real-ti...

cardiovascular disease remains the principal cause of death in the modernized world.   several novel noninvasive imaging techniques have been recently developed to improve diagnosis of cardiac and coronary disease.   of these advances, multidetector computed tomographic (mdct) angiography has evolved most dramatically to transform computed tomography from a single-slice trans-axial modality to ...

Electron microscopy played a key role in establishing cell biology as a discipline, by producing fundamental insights into cellular organization and ultrastructure. Many seminal discoveries were made possible by the development of new sample preparation methods and imaging modalities. Recent technical advances include sample vitrification that faithfully preserves molecular structures, three-di...