Background The strikingly young age of new variant Creutzfeldt-Jacob disease (vCJD) cases remains unexplained. Age dependent susceptibility to infection has been put forward, but differential dietary exposure to contaminated food products in the UK population according to age and sex during the bovine spongiform encephalopathy (BSE) epidemic may provide a simpler explanation. Methods Using rece...

The European Commission asked EFSA to revise the guidance on risk assessment for honey bees, bumble bees and solitary Regulation (EU) 1107/2009. document is a review of EFSA's existing document, which was published in 2013. outlines approach exposure estimation different scenarios tiers. It includes hazard characterisation provides methodology covering dietary contact exposure. also recommendat...

Aims Vitamin D levels are inversely related to blood pressure. Given that low sun exposure can create a greater reliance on dietary sources of vitamin D, we aimed to determine whether dietary vitamin D and blood pressure associations differ between periods of low and high sun exposure. Methods Dietary intake, vitamin supplementation, blood pressure, and anthropometric parameters were assessed e...

BACKGROUND Previous U.S. population modeling studies have reported that urinary cadmium (Cd) excretion patterns differ with age, sex, and dietary exposure; associations between Cd exposures and health outcomes also have differed by age and sex. Therefore, it is important to test models used to estimate Cd exposures across an expanded Cd-exposure range. OBJECTIVES We estimated relative Cd expo...

CONTEXT Hepatocellular carcinoma (HCC) is one of the most common cancers in the world but with a striking geographical variation in incidence; most of the burden is in developing countries. This geographic variation in HCC incidence might be due to geographic differences in the prevalence of various etiological factors. EVIDENCE ACQUISITION Here, we review the epidemiological evidence linking...

The general population is constantly exposed to a mixture of endocrine disrupters (ED), mainly through the food chain.The dietary exposure pathways are diverse, since ED can: i) affect diet components most liable to environmental pollution (e.g., polychlorinated and polybrominated chemicals in lipid-rich foods); ii) be employed in food production (e.g., certain groups of agrochemicals); iii) be...

Published or unpublished data sets on individual occupational exposure situations are frequently combined and used for some wider purpose, either hazard evaluation or standards setting. This paper describes a model by which such individual data sets for occupational aerosol exposures might be evaluated in terms of their usefulness in this regard. For workplace aerosols, the model is centered ar...

Diets containing coho salmon (Oncorhynchus kisutch Walbaum) from the Pacific Ocean or from Lakes Erie, Michigan, and Ontario [containing a gradation from low to high of halogenated aromatic hydrocarbons, (HAHs)] were fed to C57B1/6 and DBA/2 mice. Following a 4-month dietary exposure to Lake Ontario salmon, both strains of mice demonstrated hepatomegaly. The ethoxyresorufin-O-deethylase (ERR) e...

Pancreatic cancer is a malignancy of poor prognosis which is mostly diagnosed at advanced stages. Current treatment modalities are very limited creating great interest for novel preventive and therapeutic options. Vitamin D seems to have a protective effect against pancreatic cancer by participating in numerous proapoptotic, antiangiogenic, anti-inflammatory, prodifferentiating, and immunomodul...

Abstract Purpose of Review Individuals with a history traumatic brain injury (TBI) are at much greater risk for developing cardiovascular disease (CVD) compared to the general population. This review discusses dietary patterns as means addressing modifiable factors following TBI exposure. Evidence-based resources practicing Physiatrists and Brain Injury Medicine specialists pertaining nutrition...