The title compound, C(6)H(9)NO(4), was prepared stereoselectively as a precursor for 1-aza-dienes in a study of hetero-Diels-Alder reactions. The configuration of the C=N double bond was found to be Z, corroborating earlier assignments of similar compounds based only on NMR and IR spectroscopic analysis.

the present study attempts to investigate the effect of thermal treatment at 180 °c for 8 hours on chemical changes, quality indexes and oxidative stability of three iranian common virgin olive oils (zard, mari and phishomi). oil samples were taken every 2h of heating treatment and assessed for fatty acid composition, conjugated diene value, carbonyl value, color index and oxidative stability i...

BACKGROUND Artemisinin derivatives are the key active ingredients in Artemisinin combination therapies (ACTs), the most effective therapies available for treatment of malaria. Because the raw material is extracted from plants with long growing seasons, artemisinin is often in short supply, and fermentation would be an attractive alternative production method to supplement the plant source. Prev...

The microbial degradation of cholic acid by Pseudomonas sp. N.C.I.B. 10590 was studied, and two major products were isolated and identified as 7 alpha, 12 beta-dihydroxyandrosta-1,4-diene-3,17-dione and 7 alpha, 12 alpha-dihydroxy-3-oxopregna-1,4-diene-20-carboxylic acid. Four minor products were isolated and evidence is given for the following structures: 7 alpha, 12 alpha-dihydroxyandrosta-1,...

We collected a native North American species, Phyllocnistis insignis (Frey & Boll) (Lepidoptera: Gracillariidae), in traps baited with a 3:1 blend of (Z,Z,E)-7,11,13-hexadecatrienal (triene) and (Z,Z)-7,11-hexadecadienal (diene), 2 components of the sex pheromone of the invasive citrus leafminer, P. citrella Stainton. No moths were caught in unbaited traps during 6 months of monitoring. We eval...

The five-membered zirconacycloallenoids 2 react rapidly with dihydrogen under mild conditions to yield the corresponding (s-cis-conjugated diene)zirconocenes 3. The reaction involves splitting of the H(2) molecule between the metal center and a ligand carbon atom.

Curcumin analogues are widely used in numerous biological disciplines. They employed the pharmaceutical sector and offer good pharmacology application prospects present era. In current study, two curcumin analogues—1,7-diphenylhepta-1,6-diene-3,5-dione (DPHDD) 1,7-bis(3,4-dimethoxyphenyl)hepta-1,6-diene-3,5-dione (BDMPHDD)—were tested vitro against bacterial strain S. aureus. The testing demons...

Diene groups in the terminal position of the lipid acyl chains undergo an irreversible cis f trans isomerization when lipid films are incubated on a solid support under an atmosphere which is adjusted to a relative humidity (RH) in the range 20% < RH < 100%. In general, isomerization and polymerization can be modulated by RH, temperature, and the phase state of the lipid. Under nearly dry condi...

BACKGROUND Microbial transformation of steroids has been extensively used for the synthesis of steroidal drugs, that often yield novel analogues, not easy to obtain by chemical synthesis. We report here fungal transformation of a synthetic steroidal drug, exemestane, used for the treatment of breast cancer and function through inhibition of aromatase enzyme. RESULTS Microbial transformation o...

Open access: Despite the exceptional level of sophistication in cross-coupling chemistry, reactions of substrates that incorporate the leaving group as an integral part into a heterocyclic scaffold are scarce. The title reaction outlines the utility of this reaction format (see scheme; acac=acetylacetonate), provides a convenient entry into stereodefined diene carboxylates, and adds a new chapt...