نتایج جستجو برای: diaphragms

تعداد نتایج: 892  

Journal: :The Journal of biological chemistry 1964
C H BEATTY R D PETERSON R M BOCEK E S WEST

Previously our laboratory demonstrated that voluntary muscle fiber groups and diaphragms from depanereatized and alloxan-diabetic rats take up leas acetoacetic acid than fiber groups and diaphragms from control animals (1, 2). The addition of glucose and insulin causes an increase in acetoacetic acid uptake by muscle fiber groups from both control and depancreatized rats. These experiments were...

Journal: :The Journal of biological chemistry 1951
R G HANSEN W J RUTTER L T SAMUELS

It has been suggested by Lundbaek and Stevenson (1) and Gilmore and Samuels (2) that the metabolism of rat diaphragm in vitro can be influenced by the dietary history of the animal. Diaphragms obtained from rats maintained on either a high fat or high carbohydrate diet were incubated in a medium containing glucose. Both laboratories reported that less glucose was removed from the medium by diap...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2012
Meaghan K Russell Mauro Longoni Julie Wells Faouzi I Maalouf Adam A Tracy Maria Loscertales Kate G Ackerman Barbara R Pober Kasper Lage Carol J Bult Patricia K Donahoe

Congenital diaphragmatic hernia (CDH) is a common (1 in 3,000 live births) major congenital malformation that results in significant morbidity and mortality. The discovery of CDH loci using standard genetic approaches has been hindered by its genetic heterogeneity. We hypothesized that gene expression profiling of developing embryonic diaphragms would help identify genes likely to be associated...

Journal: :The Korean journal of parasitology 2007
Carmen Ramírez-Melgar Alberto Gómez-Priego Jorge-Luis De-la-Rosa

The application of Giemsa technique to stain compressed diaphragm samples obtained from rodents experimentally infected with Trichinella spiralis is described. Diaphragm samples from rats heavily infected with 20 muscle larvae per gram of body weight (20 ML/gbw) were cut into several pieces and stained with Giemsa; on the other hand, whole diaphragms from slightly infected mice (1 ML/gbw) were ...

Journal: :The Journal of Cell Biology 2002
Elisabeth R. Barton Linda Morris Antonio Musaro Nadia Rosenthal H. Lee Sweeney

Duchenne muscular dystrophy is an X-linked degenerative disorder of muscle caused by the absence of the protein dystrophin. A major consequence of muscular dystrophy is that the normal regenerative capacity of skeletal muscle cannot compensate for increased susceptibility to damage, leading to repetitive cycles of degeneration-regeneration and ultimately resulting in the replacement of muscle f...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2004
Stefan Matecki Ghiabe H Guibinga Basil J Petrof

Duchenne muscular dystrophy is characterized by myofiber necrosis, muscle replacement by connective tissue, and crippling weakness. Although the mdx mouse also lacks dystrophin, most muscles show little myofiber loss or functional impairment. An exception is the mdx diaphragm, which is phenotypically similar to the human disease. Here we tested the hypothesis that the mdx diaphragm has a defect...

Journal: :American journal of reproductive immunology 2009
Deborah J Anderson D'Nyce L Williams Susan A Ballagh Kurt Barnhart Mitchell D Creinin Daniel R Newman Frederick P Bowman Joseph A Politch Ann C Duerr Denise J Jamieson

OBJECTIVE Diaphragms are being considered for use with vaginal microbicide gels to provide enhanced protection against sexually transmitted pathogens. The purpose of this study was to determine whether use of a diaphragm with microbicide or placebo gel causes cervicovaginal inflammation or perturbations in cervicovaginal immune defense. METHOD OF STUDY Eighty-one non-pregnant women were rando...

Journal: :Journal of applied physiology 1997
S N Hussain Q El-Dwairi M N Abdul-Hussain D Sakkal

Nitric oxide (NO), an important messenger molecule with widespread actions, is synthesized by NO synthases (NOS). In this study, we investigated the correlation between fiber type and NOS activity among ventilatory and limb muscles of various species. We also assessed the presence of the three NOS isoforms in normal skeletal muscles and how various NOS inhibitors influence muscle NOS activity. ...

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