[Purpose] The purpose of this study was to examine effects of diaphragm breathing exercise applied on the basis overload principle on respiratory function. [Subjects and Methods] The subjects of this study were 35 normal adults. They were randomly assigned to two group; the maneuver-diaphragm exercise group and self-diaphragm exercise group. The respiratory function was evaluated using the Card...

In congestive heart failure (CHF), diaphragm weakness is known to occur and is associated with myosin loss and activation of the ubiquitin-proteasome pathway. The effect of modulating proteasome activity on myosin loss and diaphragm function is unknown. The present study investigated the effect of in vivo proteasome inhibition on myosin loss and diaphragm function in CHF rats. Coronary artery l...

Main results 2 trials met the selection criteria: 1 trial compared the Prentif Cavity Rim Cervical Cap (Lamberts Ltd, Oxford, UK) with the Ortho diaphragm (Ortho Pharmaceutical Corporation, Raritan, NJ, USA) (n=1529, 6–24 mo follow up), and 1 trial compared the FemCap cervical cap (rubber manufactured by Hi-Tech Rubber, Anaheim, CA, USA) with the All-Flex diaphragm (Ortho) (n=841, 28 wk follow ...

During the past 10 years, intensive experimental research has focused on the effects of mechanical ventilation on the diaphragm. Whatever the animal species studied, all these studies have consistently shown that mechanical ventilation impaired diaphragm function, resulting in the so-called ventilatorinduced diaphragm dysfunction (VIDD) [1–9]. The development of this effect is rapid and worsens...

We investigated the dependence of electromechanical coupling and the piezoelectric response of a micromachined Pb(Zr₀.₅₂Ti₀.₄₈)O₃ (PZT) diaphragm on its curvature by observing the impedance spectrum and central deflection responses to a small AC voltage. The curvature of the diaphragm was controlled by applying air pressure to its back. We found that a depolarized flat diaphragm does not initia...

The diaphragm is a sheet of muscle that separates the lungs from the abdomen. When a person takes a deep breath, the dome-shaped diaphragm contracts and flattens. In doing this, the diaphragm pulls air into the lungs. The left diaphragm contains a small hole through which passes the tube-shaped esophagus that carries food and liquid to the stomach. Normally this hole, called a hiatus, is small ...

Inspiratory muscle weakness in patients with COPD is of major clinical relevance. For instance, maximum inspiratory pressure generation is an independent determinant of survival in severe COPD. Traditionally, inspiratory muscle weakness has been ascribed to hyperinflation-induced diaphragm shortening. However, more recently, invasive evaluation of diaphragm contractile function, structure, and ...