background: saffron is the dried stigmata of the flowers of saffron (crocus sativus l., iridaceae). saffron is well known for the treatment of gastric disorders in traditional medicine.   objectives: in the search for new potential antiulcer agents, the effects of the ethanol extract of saffron and its active constituents crocin and safranal as compared with omeprazole against gastric ulcer ind...

It is estimated that approximately 15% of diabetic people world-wide will at some stage develop diabetic foot ulceration. The prevalence of active foot ulceration varies from approx‐ imately 1% in certain European and North American studies to more than 11% in reports from some African countries (table 1). Although there have been many developments in recent years which encourage optimism for f...

Background: Patients with diabetic foot ulcer (DFU) usually have a poor quality of life (QoL) and self-efficacy, which is affected by many risk factors. However, the role psychological resilience in QoL self-efficacy DFU patients has remained unclear.

OBJECTIVE To compare risks of lower-extremity amputation between patients with Charcot arthropathy and those with diabetic foot ulcers. RESEARCH DESIGN AND METHODS A retrospective cohort of patients with incident Charcot arthropathy or diabetic foot ulcers in 2003 was followed for 5 years for any major and minor amputations in the lower extremities. RESULTS After a mean follow-up of 37 +/- ...

OBJECTIVE The aim was assessment of diabetic foot ulcer risk factors according to International Working Group on the Diabetic Foot (IWGDF) consensus. METHODOLOGY All referred patients with diabetes were divided into four groups based on IWGDF criteria (without neuropathy, with neuropathy, neuropathy with deformity or vascular disorders, foot ulcer or amputation history). RESULTS Mean age of...

Amongst the many other chronic complications, diabetes can cause impaired wound healing and, with it, increased morbidity. Up to 25% of all patients with diabetes will develop a foot ulcer and, each year in Australia, approximately 3000 persons with diabetes require amputation secondary to foot ulceration 1. The essential components of diabetic foot ulcer treatment include increasing blood supp...

Aim: To assess the efficiency of topical phenytoin compared to conventional wound care in improving the healing process in diabetic ulcers and prove that topical phenytoin can be used as relatively low cost, case of use and a better alternate in management diabetic ulcers. Material and methods: This is a prospective randomised comparative study where data from 100 patients with diabetic ulcer c...

Clinical background In diabetic patients, especially if elderly, skin ulcers of the foot are among the most debilitating complications. The main risk factors for the ulcer development are diabetic neuropathy (sensory, autonomic), lower limb ischemia (diabetic arteriopathy), limited mobility and altered plantar pressure. The aim of the study was to evaluate the different sites of the diabetic ul...

OBJECTIVE Diabetes may influence the outcome of complicated peptic ulcer disease, due to angiopathy, blurring of symptoms, and increased risk of sepsis. We examined whether diabetes increased 30-day mortality among Danish patients hospitalized with bleeding or perforated peptic ulcers. RESEARCH DESIGN AND METHODS This population-based cohort study took place in the three Danish counties of No...

OBJECTIVE Foot ulceration is a serious complication of diabetes, and new techniques that can predict wound healing may prove very helpful. We tested the ability of medical hyperspectral technology (HT), a novel diagnostic scanning technique that can quantify tissue oxy- and deoxyhemoglobin to predict diabetic foot ulcer healing. RESEARCH DESIGN AND METHODS Ten type 1 diabetic patients with 21...