The effect of eight weeks aerobic training with Propolis on some mitochondrial biogenesis markers in cardiac tissue ovariectomized diabetic rats

Objective: Atorvastatin has the pleiotropic effects, including anti-inflammation and antioxidant. Therefore, this study considered to examine the effects of atorvastatin on NF-қB expression, as a main transcription factor for expression of inflammatory cytokines, in hyperglycemia-induced nephropathy in rat. Materials and Methods: Twenty four male Wistar rats were randomly divided into four g...

considering the anti-diabetic potential of trigonella foenum-graecum (tfg) and its beneficial effect on aortic reactivity of diabetic rats, this study was conducted to evaluate the effect of its alcoholic seed extract on aortic reactivity and also figure out mechanisms including the role of adrenergic and angiotensinergic systems in streptozotocin-diabetic rats. male wistar rats were divided in...

introduction: neuropathic pain is one of the common complications of diabetes mellitus which is caused by impairment in nerve conductivity. the role of flavonoid and polyphenol compounds in treatment of neuropathic pain has been revealed, and extract of onion contains significant amounts of these compounds. the aim of this study was to investigate the effect of alcoholic extract of onion on dia...

diabetes mellitus is a chronic disease which affects the healing ability of the pulp and periodontium. the aim of the present study was to assess the histopathologic response of dental pulp to pulp capping using mta or cem cement in diabetic rats. thirty two wistar male rats aged between 8 and 10 weeks (weight: 200-250g) were divided into two groups of diabetic (n=16) and healthy (n=16) animals...

background: diabetes is a major public health problem. the development of new therapies that are able to improve glycemia management and even to cure diabetes is of great interest. in this study, protective effects of sodium tungstate against stz-induced beta-cell damages were investigated. methods: sixty rats were divided into six groups: control, diabetic, sodium tungstate treated diabetic ra...

due to the anti-diabetic and antioxidant activity of green tea epigallocatechin-gallate (egcg), this research study was conducted to evaluate, for the first time, the efficacy of chronic treatment of egcg on alleviation of hyperalgesia in streptozotocin-diabetic (stz-diabetic) rats. male wistar rats were divided into control, diabetic, egcg-treated-control and diabetic and sodium salicylate (ss...

objective(s):diabetes plays an important role in the induction of the liver injury. grape seed proanthocyanidin (gsp) have a wide range of medicinal properties against oxidative stress. in this study we evaluated antioxidant effects of gsp on liver in streptozotocin-induced diabetic rats. materials and methods: thirty male sprague–dawley rats were divided into three groups: control, untreated d...

The effects of Delonix regia extract (d200mg, d300mg, and d400mg), metformin (m8.3mg, m12.5mg and m16.5mg), pioglitazone (p0.5mg, p0.7mg and p0.9mg) and combined formulation of metformin and extract (m6.25d150mg) on glycated hemoglobin status in streptozotocin-induced diabetic Albino wistar rats. Diabetic status of these rats was assessed by estimating fasting blood glucose levels. A total of 1...

the present study was undertaken to determine whether two-month treatment of streptozotocin (stz)-diabetic rats with aqueous leaf extract of trigonella foenum-graecum (tfg 200 mg/kg i.p.) could improve thoracic aortic responsiveness and to evaluate its endothelium dependency. for this purpose, vascular responses to kcl and noradrenaline (na) were measured. diabetic state significantly increased...