Diabetic nephropathy is the most common cause of end-stage renal disease (ESRD) in the United States, and accounts for 35% of all the patients with ESRD entering a dialysis program; 63% of patients with diabetic nephropathy have type II diabetes mellitus. Hypertension is a major risk factor for renal disease and is common in people with diabetes mellitus. Strategies for preventing the progressi...

The association of diabetes mellitus and insulinoma is unusual. We are reporting the case of a 58 years old patient having diabetes mellitus type 2 for several years. This patient was well balanced with oral anti-diabetic treatment. However, the diagnosis of insulinoma was discussed due to recent episodes of hypoglycemia that persisted even after stopping the treatment. Abdominal CT allowed the...

CONTEXT Atypical antipsychotic agents are associated with diabetes mellitus and pancreatitis. Aripiprazole, a new antipsychotic, has never been implicated to cause either diabetes mellitus or pancreatitis. We present a patient who developed diabetes mellitus after being started on aripiprazole. CASE REPORT A 33 year-old male with schizophrenia presented with fatigue, dyspepsia and epigastric ...

Free radicals are increasingly formed in diabetes mellitus by the auto oxidation of glucose and glycosylated proteins. Oxidative stress and proteinglycosylation are closely related processes and have been shown to contribute to the development of complications in diabetes mellitus. The extent of protein glycosylation was assessed in alloxan induced diabetic rats after being treated with 50 mg o...

Abstract Background Painful diabetic neuropathy is one of the most common complications type 2 diabetes mellitus, with approximately 30–50% people will experience neuropathy. Chronic hyperglycemia cause an inflammatory process that trigger immune response included leukotrienes. Leukotriene B4 associated hemoglobin glycation levels. This study aimed to determine high serum leukotriene levels and...

Diabetes mellitus is among ten leading cause of death in high-income countries and it is increasing rapidly in countries undergoing industrialization. Diabetes alone claims on the average around 8% of total health budgets in developed countries [1]. Complications include diabetic retinopathy, renal failure, heart disease, diabetic neuropathy and foot ulceration and amputation. More than 90% of ...

BACKGROUND Diabetes mellitus is a heterogeneous group of disorders characterized by abnormalities of carbohydrate, protein and lipid metabolism. Type 1 diabetes mellitus is an autoimmune disease caused by destruction of pancreatic beta cells and characterized by defect in insulin secretion while type 2 diabetes mellitus results from abnormalities in insulin secretion and/or insulin action or bo...

Objectives: Estimating the possible causes of arthropathies in patients with type 2 diabetes mellitus attending outpatient clinics of internal medicine department at Menoufia university hospital. Background: Diabetes mellitus (DM) is a chronic disease and has become one of the main threats to human health in recent decades. Diabetes worldwide was estimated at between 151 million and 171 million...

OBJECTIVE The aim of the study was to estimate the prevalence of diabetic retinopathy in an urban Indian population older than 40 years. DESIGN A population-based cross-sectional study. PARTICIPANTS Five thousand nine hundred ninety-nine subjects residing in Chennai, India, were enumerated. METHODS A multistage random sampling, based on socioeconomic criteria, was followed. Identified sub...