نتایج جستجو برای: derived macrophages

تعداد نتایج: 541883  

2016
Genki Suenaga Tokunori Ikeda Yoshihiro Komohara Koutaro Takamatsu Tatsuyuki Kakuma Masayoshi Tasaki Yohei Misumi Mitsuharu Ueda Takaaki Ito Satoru Senju Yukio Ando

We hypothesized that tissue-resident macrophages in familial amyloid polyneuropathy (FAP) patients will exhibit qualitative or quantitative abnormalities, that may accelerate transthyretin (TTR)-derived amyloid deposition. To evaluate this, we examined the number and subset of tissue-resident macrophages in heart tissue from amyloid-deposited FAP and control patients. In both FAP and control pa...

Journal: :Infection and immunity 1994
X Zhang E W Alley S W Russell D C Morrison

Bacterial lipopolysaccharide and some cytokines can activate macrophages to secrete nitric oxide. Macrophage-derived nitric oxide is a key cytotoxic factor for microbicidal and tumoricidal processes. We report here that a monoclonal antibody specific for beta interferon inhibited lipopolysaccharide-induced nitric oxide production in thioglycolate-elicited C3HeB/FeJ peritoneal macrophages and ma...

Journal: :Arteriosclerosis and thrombosis : a journal of vascular biology 1994
J A Contreras M A Lasunción

Cholesteryl ester-laden macrophages are the hallmark of the fatty streaks that precede arteriosclerotic plaques in humans and experimental animals. This article studies several aspects of cytoplasmic cholesteryl ester metabolism in cultured human monocyte-derived macrophages. Adenosine 3',5'-cyclic monophosphate (cAMP) consistently inhibited cholesteryl ester mobilization from cells that had be...

Journal: :Infection and immunity 1990
R E Price J W Templeton R Smith L G Adams

The role of bovine mammary macrophages and peripheral blood monocyte-derived macrophages in natural resistance to bovine brucellosis was evaluated. A group of 11 naturally resistant and 10 chronically infected susceptible cows was studied following challenge with Brucella abortus. Macrophages from a greater proportion (P less than 0.026) of naturally resistant cows were significantly superior t...

2017
Dominik Rückerl Sharon M Campbell Sheelagh Duncan Tara E Sutherland Stephen J Jenkins James P Hewitson Tom A Barr Lucy H Jackson-Jones Rick M Maizels Judith E Allen

Rapid reprogramming of the macrophage activation phenotype is considered important in the defense against consecutive infection with diverse infectious agents. However, in the setting of persistent, chronic infection the functional importance of macrophage-intrinsic adaptation to changing environments vs. recruitment of new macrophages remains unclear. Here we show that resident peritoneal macr...

Journal: :Arteriosclerosis, Thrombosis, and Vascular Biology 2007

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