The tumor microenvironment, including cancer-associated fibroblasts (CAF), has developed as an important target for understanding tumor progression, clinical prognosis and treatment responses of cancer. Cancer cells appear to transform normal fibroblasts (NF) into CAFs involving direct cell-cell communication and epigenetic regulations. This review summarizes the current understanding on miR in...

In this paper, an interconnected power system is proposed for Automatic Generation Control (AGC) in restructured power environment. The customized AGC scheme is projected in deregulated environment for multi-source combination of hydro, reheat thermal and gas generating units in entire area. Proportional integral derivative controller is offered for AGC scheme and the gains are optimised throug...

In a deregulated environment of the power market, in order to lower their energy price and guarantee the stability of the power network, appropriate transmission lines have to be considered for electricity generators to sell their energy to the end users. This paper proposes a game-theoretic power transmission scheduling for multiple generators to lower their wheeling cost. Based on the embedde...

The identification of deregulated modules (such as induced by oncogenes) is a crucial step for exploring the pathogenic process of complex diseases. Most of the existing methods focus on deregulation of genes rather than the links of the path among them. In this study, we emphasize on the detection of deregulated links, and develop a novel and effective regulatory path-based approach in finding...

Purpose The purpose is to describe new business opportunities within the Swedish railway industry and support development of models that corresponds with needs requirements Industry 4.0, here denoted as Service Management 4.0. Design/methodology/approach study an in-depth descriptive case system specific focus on a vehicle maintainer. Public reports, statistics, internal documents, interviews d...

Tumor microenvironment including cancer-associated fibroblasts (CAF) has developed as an important target for understanding tumor progression, clinical prognosis and treatment responses of cancer. Cancer cells appear to transform normal fibroblasts (NF) into CAFs involving direct cell-cell communication and epigenetic regulations. This review summarizes the current understanding on miR involvem...

Utilities participating in deregulated markets observe increasing uncertainty in load (i.e., demand for electric power) and prices for fuel and electricity on spot and contract markets. This study proposes a new formulation of the unit commitment problem of electric power generators in a restructured electricity market. Under these conditions, an electric power generation company will have the ...