Allergens are initiators of both innate and adaptive immune responses. They are recognised at the site of entry by epithelial and dendritic cells (DCs), both of which activate innate inflammatory circuits that can collectively induce Th2 immune responses. In an attempt to have a better understanding of the role of carbohydrates in the recognition and uptake of allergens by the innate immune sys...

Hadacidin 2 und seine Monoalkalisalze 3 wurden nach Literaturangaben dargestellt. Das nach 1. c. 1 gewonnene Produkt muß jedoch durch Extraktion mit siedendem Äther und nachfolgende Umfällung mit Chloroform/Petroläther (1 : 4) aus Acetonlösung gereinigt werden. Die IR-Spektren wurden mit Infrarotspektrometern IR-10 (4000 — 300 c m 1 , KBr-Preßlinge) und IR-11 (700 — 33 c m 1 , Nujolaufschlämmun...

A multicentre, prospective cohort study of childhood asthma was established in three European countries; the purpose of the project is the examination of factors which modify the relationship between allergen exposure in infant life and subsequent atopy and asthma. Dust samples were collected from the homes of 643 infants in a single town in the UK (the first cohort) and assayed for house dust ...

Astragaloside IV (AS-IV) has been noted for its reduction of eosinophilic airway inflammation in a murine model of chronic asthma. To gain a better understanding of the mechanisms involved in this anti-inflammatory phenomenon, the effect of AS-IV on human blood eosinophils was studied in vitro. Eosinophils were isolated from the blood of patients with mild atopic asthma, preincubated with AS-IV...

ii Gutachter 1. 2. 3. Liste der wichtigsten Symbole ∆n Differenz der Stimmenzahlen für eine und die entgegengesetzte Klasse A i Klasse B free Bonferroni-Multiplikator l i β Regel c Anzahl von originalen Kategorien C k Untermenge der Objekten D i (∆n) Dispersion von ∆n, IG (W, x) Information Gain γ (A i) Wahrscheinlichkeit, dass das Objekt k zur Klasse A i-gehören wird γ i (l i β) Maß der Kreuzu...

Behaviour of Distributed Executions with Applications to Visualization Vom Fachbereich Informatik der Technischen Hochschule Darmstadt zur Erlangungen des Grades eines Doktors der Ingenieurwissenschaften (Dr.-Ing.) genehmigte Dissertation von Dipl.-Wirtsch.-Inf. Thomas Kunz aus Bad Kreuznach Referent: Prof. Dr. E. Helmut Waldschmidt 1. Korreferent: Prof. Dr. James P. Black 2. Korreferent: Prof....

Background House dust mites (HDM), including Dermatophagoides pteronyssinus (Dpt) and Dermatophagoides farinae (Df), are one of the commonest aeroallergens worldwide eliciting allergic manifestations [1]. Allergenic phenomenon is tightly associated both with the mites themselves and with ligands derived from mite-associated bacterial/fungal products. Some Dpt allergens belong of lipid-binding p...