BACKGROUND Congenital unilateral absence of the vas deferens occurs in 0.5%-1.0% of males. It has been associated with various genitourinary abnormalities, including renal agenesis. We report a case of congenital unilateral absence of the vas deferens found incidentally during vasectomy in a patient with known unilateral renal agenesis. CASE PRESENTATION A 24-year-old male presented to our ur...

Between 1994 and 2010, a total of 123 patients with obstructive azoospermia due to aplasia of vas deferens (CAVD) were surgically treated. In 110 patients, the condition was bilateral (CBAVD), 13 men had unilateral aplasia (CUAVD), and 10 patients additionally had aplasia of one kidney. All patients underwent CFTR genetic testing, which detected two mutations (homozygous or compound heterozygou...

Abstract Introduction Obstructive azoospermia accounts for up to 14% of patients presenting fertility evaluation. Fine-needle vasography (FNV) is a diagnostic procedure that can be performed identify an obstruction proximal the ejaculatory duct. Compared traditional vasography, FNV utilizes less-invasive method perform imaging vas deferens and distal structures. Herein we report our experience ...

BACKGROUND Cimetidine, histamine H2 receptors antagonist, has caused adverse effects on the male hormones and reproductive tract due to its antiandrogenic effect. In the testes, peritubular myoid cells and muscle vascular cells death has been associated to seminiferous tubules and testicular microvascularization damages, respectively. Either androgen or histamine H2 receptors have been detected...

Aluminium is a blocker of voltage sensitive cakcium channels which intere the body from different soueces.this ion interferes with biological function of Ca++ion.because GnRH synthesis,secretion and spermatogenesis on vas deferens and epididymis sperm count and weight of these organs in male rats.the study was performed on four group of rats(n=49),in whom the arcuate nuleus was bilateraly cannu...

Inactivation of dynorphin-(1-8) in three in vitro isolated preparations, guinea-pig ileum, mouse vas deferens and rabbit vas deferens, was estimated by employing the relatively specific inhibitors of enkephalin-hydrolyzing enzymes. All three enzyme inhibitors, amastatin, captopril and phosphoramidon, significantly enhanced the inhibitory potency of dynorphin-(1-8) in the three isolated preparat...

BACKGROUND Relaxin is the endogenous ligand of the G-protein coupled receptor RXFP1, previously known as LGR7. In humans relaxin can also activate, but with lower affinity, the closely related receptor for the insulin-like peptide from Leydig cells, RXFP2, previously known as LGR8. The lack of relaxin impairs male fertility but the precise distribution and the function of relaxin receptors in t...

Although men who have CF can enjoy a normal sex life, they are almost always (in about 98% of cases) infertile due to failure of the vas deferens, the tube which carries sperm from the testis to the penis, to develop properly (Kaplan et al, 1968). The epididymis sits on top of the testis like a cap. Normally the vas deferens carries the newly made sperm to the back of the prostate gland where i...

Vasectomy is an elective surgical sterilization procedure for men that is intended to obstruct or remove a portion of both vas deferens, thereby preventing sperm from moving from the testes to the ejaculatory ducts. Although intended for permanent sterilization, vasectomy can be reversed in most men seeking to restore their fertility due to a change in marital status or reproductive goals. The ...