Liver transplantation was approved for treatment of decompensated cirrhosis in the United States in 1983. Hepatitis B and hepatitis C viruses are the leading causes of liver transplantation for viral hepatitis and hepatitis B is also an important cause of liver transplantation for called acute liver failure) due to either acute hepatitis B or an acute exacerbation of chronic hepatitis B. Howeve...

BACKGROUND The treatment of chronic hepatitis C virus infection has been revolutionized by the advent of direct-acting antiviral agents. However, evidence of its effects on patients with acute hepatitis C (AHC) virus infection is limited. CASE SUMMARY We report the case of a patient with decompensated cirrhosis induced by autoimmune liver disease, whose condition rapidly deteriorated followin...

The modern paradigm considers cirrhosis as a dynamic and potentially reversible disease. It consists of two different entities, compensated and decompensated cirrhosis, each with a distinct prognosis and different predictors of survival. The development of portal hypertension is a hallmark in the history of cirrhosis, and its progression parallels that of the disease. In consequence, portal pre...

Herein, we describe two patients who underwent liver transplantation with the clinical diagnosis of hepatic failure and cryptogenic cirrhosis; histopathology of the explanted hepatectomy specimen revealed congenital hepatic fibrosis. To the best of our knowledge, coexistence of hepatic failure and cirrhosis in congenital hepatic fibrosis, have not yet been reported in the English literature.

BACKGROUND Although there are many studies of the predictors of death in hepatocellular carcinoma (HCC), most combine patients with and without cirrhosis and many combine those with compensated and decompensated cirrhosis. OBJECTIVE To perform a systematic review of the literature evaluating the predictors of death in patients with cirrhosis and HCC and to evaluate whether the predictors diff...

Background Hepatitis B viral represents a pathology with a severe impact on public health. Worldwide, approximately 350 million individuals are chronically infected with hepatitis B virus (HBV). HBV is the leading cause of cirrhosis globally. Once chronic infection is established, approximately 30% of the patients will develop cirrhosis, and approximately one-quarter of patients with cirrhosis ...

Chronic hepatitis C infection is an important cause of cirrhosis and hepatocellular carcinoma (HCC). Antiviral therapy (AVT) for patients with cirrhosis due to hepatitis C may retard the progression of cirrhosis and prevent both the development of HCC as well as the recurrence of hepatitis C following liver transplantation. This review highlights the issues associated with AVT for patients with...

In a series of 535 autopsies performed in the King George's Medical College Hospital, Vizagapatam, there were 50 cases (9.3 per cent) of cirrhosis of the liver. The material in this paper is based on a critical study of the autopsy findings in these 50 cases. The causes of cirrhosis of the liver in the 50 cases under discussion are given in the table. It will thus be seen from the table that, o...