Choroidal osteoma is a unique tumor that comprises mature bone in the circumpapillary or macular region.1 Choroidal osteoma showed evolution with change in clinical features over many years, and cases of tumor growth, tumor decalcification or involution, and related choroidal neovascularization (CNV) were documented.1-4 Herein, we present a case of choroidal osteoma with serous retinal detachme...

To assess bone pathologies and bone regeneration immunohistochemistry may provide additional information compared to conventional histology. However, the effectiveness of this technique is limited due to tissue fixation, preparation and embedding. For bone tissue the standard immunohistological procedure includes formalin fixation, followed by decalcification and paraffin embedding. This may le...

BACKGROUND AND PURPOSE The possible relationship of orbit deformities in neurofibromatosis type 1 (NF1) to plexiform neurofibromas (PNFs) have not been fully elucidated. Our purpose was to review orbital changes in patients with craniofacial NF1. METHODS We retrospectively reviewed CT and MR imaging abnormalities of the orbit in 31 patients (18 male, 13 female; mean age, 14 years; age range 1...

INTRODUCTION Decalcification is the commonly employed technique in histopathology laboratories as a part of calcified tissue preparation for the microscopic examination. Chemical agents are most commonly used for routine decalcification procedures, though some agents adversely affect the tissue integrity and staining properties. AIM To compare the efficacy of various decalcifying agents by hi...