BACKGROUND Organotins are highly toxic and widely distributed environmental chemicals. Dibutyltin (DBT) is used as stabilizer in the production of polyvinyl chloride plastics, and it is also the major metabolite formed from tributyltin (TBT) in vivo. DBT is immunotoxic, however, the responsible targets remain to be defined. Due to the importance of glucocorticoids in immune-modulation, we inves...

Studies with mammograms have demonstrated a relationship between parenchymal texture and breast cancer risk. Although promising, texture analysis in mammograms is limited by the effect of tissue superimposition. Digital Breast Tomosynthesis (DBT) is a novel tomographic x-ray breast imaging modality that alleviates the effect of tissue superimposition. We explore the potential advantages of DBT ...

Domain Based Testing (DBT) uses Domain Analysis and a Domain Model to automate test generation for command-based systems. Instead of using a Domain Model for reuse, we use it as a structure to generate test cases. Part of the Domain Model for DBT includes the syntax and semantics of the command language. Domain Based Testing separates command language syntax from command language semantics. The...

Societal cost-of-illness in a German sample of patients with borderline personality disorder (BPD) was calculated for 12 months prior to an outpatient Dialectical Behavior Therapy (DBT) program, during a year of DBT in routine outpatient care and during a follow-up year. We retrospectively assessed resource consumption and productivity loss by means of a structured interview. Direct costs were ...

OBJECTIVE This treatment development study investigated the acceptability and efficacy of a modified version of dialectical behavior therapy (DBT) for bulimia nervosa (BN), entitled appetite focused DBT (DBT-AF). METHOD Thirty-two women with binge/purge episodes at least one time per week were randomly assigned to 12 weekly sessions of DBT-AF (n = 18) or to a 6-week delayed treatment control ...

Mutations lowering the kinase activity of Drosophila Doubletime (DBT) and vertebrate casein kinase Iepsilon/delta (CKIepsilon/delta) produce long-period, short-period, and arrhythmic circadian rhythms. Since most ckI short-period mutants have been isolated in mammals, while the long-period mutants have been found mostly in Drosophila, lowered kinase activity may have opposite consequences in fl...

Dialectical behavior therapy (DBT) was born out of necessity to help suicidal individual ssuffering from severe emotion dysregulation. DBT evolved into a comprehensive, modular and hierarchical treatment consisting of a numerous treatment modes (i.e., individual psychotherapy, group skills training, out-of-session coaching, and a clinician consultation team). DBT is an intensely studied treatme...

Dialectical behavior therapy (DBT) has received strong empirical support and is practiced widely as a treatment for borderline personality disorder (BPD) and BPD with comorbid substance use disorders (BPD-SUD). Therapeutic success in DBT requires that individuals generalize newly acquired skills to their natural environment. However, there have been only a limited number of options available to...

The purpose of this dissertation is to explore the experiences and utilization of Certified Peer Support Specialists employed on Dialectical Behavior Therapy teams. Trends in the literature regarding peer support include the challenges faced by Peer Support Specialists, the benefits peers gained by employment, and solutions for ongoing peer program development. There is also an abundance of stu...

Dialectical Behavior Therapy (DBT) is an evidence-based treatment for borderline personality disorder that has been widely disseminated to many outpatient treatment settings. Many practitioners depend on third-party payers to fund treatment delivery. DBT requires additional clinical services not often included in outpatient therapy, including a weekly skills group led by 2 clinicians, and the r...