Training opportunities for working journalists have become a common feature of the professional environment in many countries. These programs–often referred to as midcareer training–are offered by the employer, by formal educational institutions, or by independent training organizations. Despite the prominence of these training programs, relatively little research has been done on the consequen...

The structural changes in the centrioles in Chinese hamster ovary cells were monitored by electron microscopy of whole mount preparations to investigate the effects of colcemid on the events in the centriole cycle. The population of mitotic cells increased with time of incubation with colcemid, but the arrest at mitosis by this drug was soon overcome, resulting in the formation of nuclei and a ...

The daughter cyst sign is a specific indicator of an uncomplicated ovarian cyst and pathologically represents a stimulated ovarian follicle. This finding must be differentiated from an ectopic pregnancy in a patient who has the potential to become pregnant. We report an uncomplicated ovarian cyst in a 3-year-old female with McCune-Albright syndrome and precocious puberty mimicking an ectopic pr...

The genetic information encoded in genomes must be faithfully replicated and transmitted to daughter cells. The recent discovery of consecutive DNA conversions by TET family proteins of 5-methylcytosine into 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxylcytosine (5caC) suggests these modified cytosines act as DNA lesions, which could threaten genome integrity. Here, we have shown tha...

Background Familial amyloid polyneuropathy (FAP ATTRV30M) is an autosomal dominant systemic amyloidosis, due to a point mutation in the transthyretin (TTR) gene (chr18q12.1). The most frequent one, V30M is associated with several clusters. Among Portuguese families, FAP shows a wide variation in in age-at-onset (AO) [19-82 yrs] and this variability is also apparent between generations. Also, si...

A long-standing problem in chromosome biology concerns the dynamic nature of centromeres. These chromosomal sites assemble the protein machines called kinetochores that connect chromosomes to the spindle microtubules for segregation to daughter cells during mitosis and meiosis. In multicelluar eukaryotes, centromeres are typically composed of highly homogeneous tandem repeats that evolve rapidl...

We discuss a nonperturbative relation for orientifold parent/daughter pairs of supersymmetric theories with an arbitrary tree-level superpotential. We show that super-Yang-Mills (SYM) theory with matter in the adjoint representation at N → ∞, is equivalent to a SYM theory with matter in the antisymmetric representation and a related superpotential. The gauge symmetry breaking patterns match in ...

Word embeddings, which represent words as dense feature vectors, are widely used in natural language processing. In their seminal paper on word2vec, Mikolov and colleagues showed that a space created by training word prediction network large text corpus will encode semantic information supports analogy vector arithmetic, e.g., "king" minus "man" plus "woman" equals "queen". To help novices appr...

Every mitosis, replicated chromosomes must be accurately segregated into each daughter cell. Pairs of sister chromatids attach to the bipolar mitotic spindle during prometaphase, they are aligned at metaphase, then sisters separate and are pulled to opposite poles during anaphase. Failure to attach correctly to the spindle before anaphase onset results in unequal segregation of chromosomes, whi...