نتایج جستجو برای: danmarane sapogenins

تعداد نتایج: 169  

Journal: :Molecules 2016
Laura García-Pupo Armando Zaldo-Castro Vassiliki Exarchou Juan Enrique Tacoronte-Morales Luc Pieters Wim Vanden Berghe Yanier Nuñez-Figueredo René Delgado-Hernández

Two spirosteroid analogues were synthesized and evaluated for their in vitro neuroprotective activities in PC12 cells, against glutamate-induced excitotoxicity and mitochondrial damage in glucose deprivation conditions, as well as their anti-inflammatory potential in LPS/IFNγ-stimulated microglia primary cultures. We also evaluated the in vitro anti-excitotoxic and anti-inflammatory activities ...

Journal: :Molecules 2017
Lingxin Xiong Zeng Qi Bingzhen Zheng Zhuo Li Fang Wang Jinping Liu Pingya Li

Enzymes involved in the coagulation process have received great attention as potential targets for the development of oral anti-coagulants. Among these enzymes, coagulation factor Xa (FXa) has remained the center of attention in the last decade. In this study, 16 ginsenosides and two sapogenins were isolated, identified and quantified. To determine the inhibitory potential on FXa, the chromogen...

2017
Xiaorui Wu Dong Li Junlian Liu Lihong Diao Shukuan Ling Yuheng Li Jianyi Gao Quanchun Fan Weijia Sun Qi Li Dingsheng Zhao Guohui Zhong Dengchao Cao Min Liu Jiaping Wang Shuang Zhao Yu Liu Guie Bai Hongzhi Shi Zi Xu Jing Wang Chunmei Xue Xiaoyan Jin Xinxin Yuan Hongxing Li Caizhi Liu Huiyuan Sun Jianwei Li Yongzhi Li Yingxian Li

Increasing evidence indicates the occurrence of cognitive impairment in astronauts under spaceflight compound conditions, but the underlying mechanisms and countermeasures need to be explored. In this study, we found that learning and memory abilities were significantly reduced in rats under a simulated long-duration spaceflight environment (SLSE), which includes microgravity, isolation confine...

2012
Renuka Kalyani

Gokshur is one of the plant used in Ayurveda.The plant has diuretic activity.Brihat gokshur and Laghu gokshur are the plants used under the mishrak varga Dashmoola. Both the varieties contains sapogenins,tannins,glycoside etc.. chemical constituents. Among these steroidal saponin is the main active principle which is responsible for the diuretic activity of the plant. The present research work ...

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