Weight gain, obesity and hyperprolactinemia are important complications of long-term administration of neuroleptic drugs, which may affect the patient's general health and well- being that itself interferes with treatment compliance. The purpose of this study was to identify the mechanism of occurrence of these side-effects. Because of the important role of ventromedial nucleus of hypothalamus ...

The mean daily fluoride intake in infants was estimated on the basis of their intake of commercial foods for infants in Japan and evaluated in order to establish the effectiveness and safety criteria for water fluoridation, which is practiced as a preventive measure for dental caries suitable in life stages from children to the elderly. Based upon the intakes of foods for infants, the mean dail...

High sodium intake can increase blood pressure and the risk for heart disease and stroke. According to the Dietary Guidelines for Americans, 2010, persons in the United States aged ≥2 years should limit daily sodium intake to <2,300 mg. Subpopulations that would benefit from further reducing sodium intake to 1,500 mg daily include 1) persons aged ≥51 years, 2) blacks, and 3) persons with hypert...