نتایج جستجو برای: daclizumab

تعداد نتایج: 624  

2016
Bishu Ganguly Balaji Balasa Lyubov Efros Paul R. Hinton Stephen Hartman Archana Thakur Joanna M. Xiong Brian Schmidt Randy R. Robinson Thierry Sornasse Vladimir Vexler James P. Sheridan

The CD25-binding antibody daclizumab high-yield process (DAC HYP) is an interleukin (IL)-2 signal modulating antibody that shares primary amino acid sequence and CD25 binding affinity with Zenapax®, a distinct form of daclizumab, which was approved for the prevention of acute organ rejection in patients receiving renal transplants as part of an immunosuppressive regimen that includes cyclospori...

Journal: :Journal of Neuroimmunology 2021

NK/T-cell ratios predict disease activity in relapsing remitting multiple sclerosis (RRMS). We investigated 50 RRMS patients whether interleukin-2 receptor alpha-chain (IL-2R?) expression and shedding associates with balance, as suggested by daclizumab-trials RRMS. A subsample (N = 31) was genotyped for IL2RA-associated MS risk SNPs. CD56bright NK-cell/IL-17A+CD4+ T-cell correlated negatively p...

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