نتایج جستجو برای: daclatasvir
تعداد نتایج: 714 فیلتر نتایج به سال:
BACKGROUND The combination of daclatasvir, a hepatitis C virus (HCV) NS5A inhibitor, and the NS5B inhibitor sofosbuvir has shown efficacy in patients with HCV monoinfection. Data are lacking on the efficacy and safety of this combination in patients coinfected with human immunodeficiency virus type 1 (HIV-1). METHODS This was an open-label study involving 151 patients who had not received HCV...
Drosophila C virus, a picornavirus that has some influence on ovarian morphogenesis, was discovered in a French strain of Drosophila melanogaster. When the strain was infected by Drosophila C virus (DCV), the mean number of ovarian tubes and weights of the adult females increased, but the developmental time from egg to imago decreased. The maternal effects observed when DCV was present disappea...
www.thelancet.com/lancetgh Vol 3 November 2015 e676 gross national income (figure). In high-income countries, the price per bottle of sofosbuvir ranged from $14 000 (Spain) to $20 590 (Switzerland). Prices for daclatasvir ranged from $1128 (South Korea) to $14 899 (Germany); those of simeprevir from $9166 (Spain) to $14 865 (Australia); those of ledipasvir-sofosbuvir from $12 604 (USA) to $24 8...
17.7. Zeuzem S, Ghalib R, Rajender Reddy K, et al.Grazoprevir–elbasvir combination therapy for treatmentnaive cirrhotic and noncirrhotic patients with chronic HCVgenotype 1, 4, or 6 infection: a randomized trial. AnnIntern Med. Published online 24 April 2015doi:10.7326/M15-0785.8. Yeh WW. Drug-drug interactions withgrazoprevir/elbasvir: practical considerations for t...
Ocean Chemistry and Ecosystems Division, Atlantic Oceanographic and Meteorological Laboratory (stationed at NOAA/NMFS/SWFSC/La Jolla, CA), National Oceanic and Atmospheric Administration, Miami, FL, USA, Department of Biological Sciences and Northern Gulf Institute, University of Southern Mississippi, Hattiesburg, MS, USA, Marine and Environmental Sciences Centre (MARE), Faculty of Sciences, Un...
Infection avoidance behaviors are the first line of defense against pathogenic encounters. Behavioral plasticity in response to internal or external cues of infection can therefore generate potentially significant heterogeneity in infection. We tested whether Drosophila melanogaster exhibits infection avoidance behavior, and whether this behavior is modified by prior exposure to Drosophila C Vi...
Daclatasvir (DCV) and asunaprevir (ASV) are direct-acting antivirals (DAAs) used in the treatment of chronic hepatitis C virus (HCV) infection. Combined therapy with DCV and ASV shows high efficacy and safety even in patients with cirrhosis. We encountered a patient exhibiting severe hyperbilirubinemia during combined therapy, which is an unreported side effect of DCV and ASV. A 78-year-old wom...
Daclatasvir and Ribavirin for 12 Weeks in Patients Infected With HCV Genotype 1b Maurizia Brunetto, MD; Khurram Rana; Gloria Taliani; Eric Lawitz; Christophe Hézode; Patrick Marcellin; Lawrence Serfaty; David Cohen; Subasree Srinivasan; Liver Unit University Hospital of Pisa, Pisa, Italy; BristolMyers Squibb, Wallingford, CT; Azienda Ospedaliera Universitaria, Policlinico Umberto I, Roma, Italy...
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