This study aims to investigate the cytotoxicity of Andrographis paniculata, Ziziphus spina-christi and Gymnanthemum extensum crude extracts their combination with low piperine fractional Piper nigrum extract. All plants were extracted water five organic solvents (methanol, ethanol, dichloromethane, ethyl acetate hexane). Cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tet...