نتایج جستجو برای: cytotoxicity activity

تعداد نتایج: 1164261  

Journal: :Folia parasitologica 2001
S Muelas R Di Maio H Cerecetto G Seoane C Ochoa J A Escario A Gómez-Barrio

The cytotoxicity of 18 new 1,2,6-thiadiazin-3,5-dione 1,1-dioxides was evaluated. This group of products was previously assayed against epimastigotes of Trypanosoma cruzi and some of them showed a high antiprotozoal activity. Thereafter 13 compounds with a high anti-epimastigote activity and low cytotoxicity were selected to be assayed against amastigotes. Some of the products showed the same o...

Journal: :Indian Journal of Pharmaceutical Sciences 2021

This study aims to investigate the cytotoxicity of Andrographis paniculata, Ziziphus spina-christi and Gymnanthemum extensum crude extracts their combination with low piperine fractional Piper nigrum extract. All plants were extracted water five organic solvents (methanol, ethanol, dichloromethane, ethyl acetate hexane). Cytotoxicity was assessed by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tet...

Erik De Clercq Khan Mohammad Sardar Yar Sadish Kumar Shanmugam, Vivek Gupta Yatendra Kumar

Brown alga, Turbinaria conoides was successively extracted with n-hexane, cyclohexane, methanol and ethanol:water (1:1). The extracts were evaluated for antibacterial and antifungal activities by disc diffusion method. Minimal inhibitory concentration was determined for active extracts by broth dilution method. The antiviral activity and cytotoxicity of the extracts were tested in human embryon...

Journal: :Blood 2003
Roland B Walter Brian W Raden Tom C Hong David A Flowers Irwin D Bernstein Michael L Linenberger

Gemtuzumab ozogamicin (GO) is a novel immunoconjugate therapy for acute myeloid leukemia (AML). P-glycoprotein (Pgp) confers resistance to GO and is associated with a worse clinical response. To address whether multidrug resistance protein (MRP) affects GO susceptibility, we characterized Pgp, MRP1, and MRP2 expression in CD33+ cell lines and CD33+ AML samples and analyzed the effect of the Pgp...

2016
L. J. Liu J. N. Liu

The rhizome of Menispermum dauricum DC known as a traditional Chinese medicine, with high content of alkaloids, has been found to possess antitumor activity. In this research, an attempt to correlate fingerprinting with bioactivity was made for quality control of M. dauricum. Firstly, the cytotoxicity of extracts from ten batches of samples against human breast MCF-7 cancer cells was estimated ...

Journal: :research in pharmaceutical sciences 0

swertia species are widespread in eastern and southern asian countries and used in traditional medicine as anti-pyretic, analgesic, gastro and liver tonic. among different species, only swertia longifolia grows in iran. in this investigation, antioxidant, cytotoxic and acetylcholinesterase inhibitory activities of s. longifolia have been studied. aerial parts and roots of the plant were collect...

TiO2-grafted cellulose bio-nanocomposite (Cell.Com) was successfully prepared by combining modified cellulose and TiO2 nanoparticles via copper-catalyzed alkyne-azide click reaction. The antibacterial and cytotoxicity effects of Cell.Com containing cellulose, triazole ring and TiO2 moieties are reported in this work. The antibacterial activity of Cell.Com was investigated against gram positive ...

Journal: :journal of applied pharmaceutical science 2022

Assessment of cytotoxicity, antibacterial activity and phytochemical screening ethanol extract Phyllanthus acidus L. (family: Euphorbiacceae) BarkSubrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan

Journal: :journal of applied pharmaceutical science 2023

Assessment of cytotoxicity, antibacterial activity and phytochemical screening ethanol extract Phyllanthus acidus L. (family: Euphorbiacceae) BarkSubrata Kumar Biswas, Anusua Chowdhury, Joysree Das, Utpal Karmakar, Manik Chandra Shill, Sheikh Zahir Raihan

2013
Ann Shine Paul Aneesul Islam P. Yuvaraj

Anti-Helicobacter pylori and cytotoxic activity of detoxified root ethanol extract of Plumbago auriculata, Plumbago indica and Plumbago zeylanica. These three Plumbaginales root were detoxified with lime water and prepared the ethanol extract. Ethanol extract of these plants are possible activity against H. pylori and cytotoxicity activity with MTT assay in HGE-17 cell lines. These three plants...

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  • "; pgn_html+=pgn_li; } document.getElementById("pgn-ul").innerHTML=pgn_html var pgn_links = document.querySelectorAll('.mypgn'); pgn_links.forEach(function(pgn_link) { pgn_link.addEventListener('click', paginate) }) } function post_and_fetch(data,url) { showLoading() xhr = new XMLHttpRequest(); xhr.open('POST', url, true); xhr.setRequestHeader('Content-Type', 'application/json; charset=UTF-8'); xhr.onreadystatechange = function() { if (xhr.readyState === 4 && xhr.status === 200) { var resp = xhr.responseText; resp_json=JSON.parse(resp) resp_place = document.getElementById("search_result_div") resp_place.innerHTML = resp_json['results'] search_meta = resp_json['meta'] update_search_meta(search_meta) update_pagination() hideLoading() } }; xhr.send(JSON.stringify(data)); } function unfilter() { url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":"unfilter", "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } function deactivate_all_bars(){ var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(bar) { bar.dataset.active = false bar.style = "stroke:#71a3c5;" }) } year_chart.on("created", function() { var yrchart = document.querySelectorAll('.ct-bar'); yrchart.forEach(function(check) { check.addEventListener('click', checkIndex); }) }); function checkIndex(event) { var yrchart = document.querySelectorAll('.ct-bar'); var year_bar = event.target if (year_bar.dataset.active == "true") { unfilter_res = unfilter() year_bar.dataset.active = false year_bar.style = "stroke:#1d2b3699;" } else { deactivate_all_bars() year_bar.dataset.active = true year_bar.style = "stroke:#e56f6f;" filter_year = chart_data['labels'][Array.from(yrchart).indexOf(year_bar)] url=/search_year_filter/ var term=document.getElementById("search_meta_data").dataset.term var data={ "year":filter_year, "term":term, "pgn":1 } filtered_res=post_and_fetch(data,url) } } function showLoading() { document.getElementById("loading").style.display = "block"; setTimeout(hideLoading, 10000); // 10 seconds } function hideLoading() { document.getElementById("loading").style.display = "none"; } -->