نتایج جستجو برای: cytotoxic t lymphocytes
تعداد نتایج: 773703 فیلتر نتایج به سال:
The progress of HIV is accompanied by the infection and decline of the population of CD4+ cells. This reduction in cells results from both cytolytic influences of the virus and virus-specific cytotoxic T-cell (CTL) responses. We seek to characterize the extent of CD4+ reduction caused by HIV-specific CTLs at equilibrium. Here we show that intermediate levels of cytotoxic killing of infected cel...
To investigate how cytotoxic T lymphocytes (CTL) avoid killing themselves when they destroy target cells, we compared 20 different cell lines as target cells, including several CTL cell lines, for their susceptibility to lysis by CTL. Variations in recognition of this diverse set of target cells was circumvented by attaching to all of them a monoclonal antibody to the antigen-specific receptor ...
1Masonic Cancer Center and Department of Pediatrics, Division of Blood and Marrow Transplantation, University of Minnesota, Minneapolis, MN; 2Department of Pathology, Harvard Medical School and Brigham and Women’s Hospital, Boston, MA; 3Department of Therapeutic Radiology, University of Minnesota, Minneapolis, MN; 4Department of Molecular Immunology, Tokyo Medical and Dental University, Tokyo, ...
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