نتایج جستجو برای: cytogenetics

تعداد نتایج: 10190  

Journal: :Journal of Medical Genetics 1993

Journal: :Pediatric Hematology Oncology Journal 2016

2001
GERALD F. SHIELDS

Avian cytogenetic research has, until recently, lagged far behind efforts devoted to the cytogenetics of other vertebrate groups. Avian chromosomes are inherently difficult to study because most are minute and their morphology and number are obscure. Since 1966, improved methods of culturing avian cells have resulted in more comparative chromosome studies whose quality parallels those for mamma...

Journal: :Haematologica 2008
Mar Mallo Leonor Arenillas Blanca Espinet Marta Salido Jesús M Hernández Eva Lumbreras Mónica del Rey Eva Arranz Soraya Ramiro Patricia Font Olga González Mónica Renedo José Cervera Esperanza Such Guillermo F Sanz Elisa Luño Carmen Sanzo Miriam González María José Calasanz José Mayans Carlos García-Ballesteros Victoria Amigo Rosa Collado Isabel Oliver Félix Carbonell Encarna Bureo Andrés Insunza Lucrecia Yañez María José Muruzabal Elena Gómez-Beltrán Rafael Andreu Pilar León Valle Gómez Angeles Sanz Natalia Casasola Esperanza Moreno Adrián Alegre María Luisa Martín Carmen Pedro Sergi Serrano Lourdes Florensa Francesc Solé

BACKGROUND More than 50% of patients with myelodysplastic syndromes present cytogenetic aberrations at diagnosis. Partial or complete deletion of the long arm of chromosome 5 is the most frequent abnormality. The aim of this study was to apply fluorescence in situ hybridization of 5q31 in patients diagnosed with de novo myelodysplastic syndromes in whom conventional banding cytogenetics study h...

Journal: :The Yale Journal of Biology and Medicine 1992
Margretta R. Seashore

To begin with, Human Pharmacology is a moderately priced book that makes no pretense to be as encyclopedic as Goodman and Gilman. One of the main advantages of the book is its consistency of presentation. Each chapter is presented in five sections: (1) therapeutic overview; (2) mechanisms of action; (3) pharmacokinetics; (4) relation of mechanisms of action to clinical response; and (5) side ef...

Journal: :Frontiers in bioscience 2012
Gail E Tomlinson

The cytogenetics of hepatoblastoma demonstrate recurring events which include whole chromosome trisomies, most commonly trisomy of chromosome 2, 8, or 10. In addition, unbalanced translocations involving a breakpoint on the proximal short arm of chromosome 1 are observed which result in a duplication of the long arm of chromosome 1q. The most commonly involved reciprocal chromosomal arm is 4q, ...

Journal: :The Ulster Medical Journal 1975
Angela I. Taylor

ALTHOUGH attempts at establishing the human chromosome number dates from early in this century, it was not until 1957 when improvements in techniques became available that human cytogenetics became established as a laboratory discipline. Since 1959, many clinical disorders ranging from abnormalities of sexual, physical and intellectual development, pregnancy wastage, leukaemia and tumours, have...

Journal: :journal of agricultural science and technology 2012
m. gaffaroğlu m. karasu s. unal

karyotype of river loach turcinoemacheilus kosswigi from the euphrates river, turkey was investigated using conventional giemsa-staining and c-banding. two females and two males were analyzed. diploid chromosome number was 2n= 50 in all specimens. the karyotype consisted of four pairs of metacentric (m), seven pairs of submeta (sm)-subtelocentric (st) and 14 pairs of acrocentric (a) chromosomes...

Journal: :acta medica iranica 0
reza shirkoohi cancer research center, cancer institute of iran, tehran university of medical sciences, tehran, iran. cyrus azimi cancer research center, cancer institute of iran, tehran university of medical sciences, tehran, iran.

cancer is a genetic-epigenetic based disease which contains a complex of alterations that cause irreversible transformation of cells with a new anarchic behavior. tumor suppressor inactivation and/or oncogene activation will lead to tumorigenesis. based on the genetic alteration in germ or somatic cells, the affected person will have a different fate of cancer incidence or inheritable cancer su...

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