نتایج جستجو برای: cytogenetic risk groups

تعداد نتایج: 1591243  

2006

Metabolic conversion of oestrogen phenolic groups may create conditions of oxidative stress accompanied by damage of cellular macromolecules including DNA. The aim of this investigation was to evaluate the cell cycle kinetics and possible cytogenetic changes in cultured human peripheral blood lymphocytes exposed to seven experimental concentrations of 17 -oestradiol (range 10 M to 10 M). Cell c...

Journal: :Journal of Hematology & Oncology 2009
Tara K Gregory David Wald Yichu Chen Johanna M Vermaat Yin Xiong William Tse

Acute myeloid leukemia (AML) is a heterogenous disorder that results from a block in the differentiation of hematopoietic progenitor cells along with uncontrolled proliferation. In approximately 60% of cases, specific recurrent chromosomal aberrations can be identified by modern cytogenetic techniques. This cytogenetic information is the single most important tool to classify patients at their ...

Journal: :international journal of management and business research 2012
ismaila adeleke ade ibiwoye folake olowokudejo

this study draws attention to the ubiquitous and borderless nature of cybercrime. it examines the prospect of introducing customized cyber insurance policy in the nigerian market. as secondary data was not available, the study conducted a survey by administering three sets of questionnaire to purposively selected top executives in four trade groups that rely heavily on internet transactions for...

Journal: :Cancer research 1998
C D Bloomfield D Lawrence J C Byrd A Carroll M J Pettenati R Tantravahi S R Patil F R Davey D T Berg C A Schiffer D C Arthur R J Mayer

Advances in the treatment of acute myeloid leukemia (AML) have occurred with the introduction of new therapies including high-dose cytarabine and the identification of powerful prognostic factors such as cytogenetics that predict for long-term outcome. To date, the prognostic impact of cytarabine dose escalation within various cytogenetic groups of AML has not been assessed. We describe 285 new...

Background and objective:Cytogenetic damage in exfoliated buccal epithelial cells due to environmental and occupational exposure is often monitored by micronucleus (MN) assay using liquid based cytology (LBC) preparations. This study was performed to evaluate MN in exfoliated buccal epithelial cells of building construction workers using LBC preparations. <strong...

Journal: :Critical reviews in oncology/hematology 2011
Francesco Marchesi Ombretta Annibali Elisabetta Cerchiara Maria Cristina Tirindelli Giuseppe Avvisati

Cytogenetic abnormalities are found in 50-60% of newly diagnosed acute myeloid leukemia (AML) of adult patients. Cytogenetic analysis of bone marrow leukemic cells is an important pre-treatment evaluation for a correct prognostic stratification of patients, that permit to separate AML patients in three broad prognostic categories: high, intermediate and low risk. The determination of cytogeneti...

Journal: :Turkish journal of haematology : official journal of Turkish Society of Haematology 2011
Milena Georgieva Velizarova Evgueniy A Hadjiev Kamelia V Alexandrova Ivanka I Dimova Draga I Toncheva Nadya E Dimitrova

OBJECTIVE Treatment of acute lymphoblastic leukemia (ALL) in adults focuses on the initial assessment of the prognostic relevant cytogenetic features as well as a response-guided therapy based on molecular data. We examined the importance of molecular-cytogenetic abnormalities for complete remission (CR) rates and the overall survival (OS) in adult ALLs. METHODS Conventional cytogenetics and ...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه علامه طباطبایی - دانشکده اقتصاد 1389

this thesis is a study on insurance fraud in iran automobile insurance industry and explores the usage of expert linkage between un-supervised clustering and analytical hierarchy process(ahp), and renders the findings from applying these algorithms for automobile insurance claim fraud detection. the expert linkage determination objective function plan provides us with a way to determine whi...

Journal: :Haematologica 2007
Ulrich Germing Corinna Strupp Sabine Knipp Andrea Kuendgen Aristoteles Giagounidis Barbara Hildebrandt Carlo Aul Rainer Haas Norbert Gattermann John M Bennett

The WHO classification moved CMML to myeloproliferative/myelodysplastic disorders, and defined CMML I and CMML II according to medullary and peripheral blast count. To confirm these proposals, we analyzed 266 patients with CMML I and 73 patients with CMML II. Median survival time was 20 months for CMML I, and 15 months for CMML II (p<0.005). The cumulative risk of AML evolution differed between...

Conventional cytogenetic is the standard technique for detection of Philadelphia (Ph) chromosome in chronic myeloid leukemia (CML). Evaluation of abelson murine leukemia/breakpoint cluster region (abl/bcr) fusion using dual-colour fluorescence in situ hybridization (D-FISH) is an alternative approach allowing rapid and reliable detection of the disease. We employed the technique of interphase D...

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