In a series of experiments to investigate interactions between industrial solvents and common medications the interaction between m-xylene and aspirin was studied. As both these substances are metabolised and excreted as glycine conjugates there would possibly be competition for this conjugation pathway. Five male volunteers were exposed on separate occasions to m-xylene by inhalation (100 ppm)...

background: xylene is known as one of the most toxic of the nervous system. the purpose of this study is to estimate the concentration of xylene in the cabin of the vehicles production in iran. also the effect of ventilation, cigarette smoking, and air freshener inside the vehicle, fuel type and car decorations on the concentration of the substance being studied.   methods: 152 vehicles pride a...

Distribution of Inhaled m-Xylene in Rat Brain and its Effect on GABAA Receptor Binding: Takehiko ITO, et al. Faculty of Education, Okayama University—Organic solvents generally depress the central nervous system (CNS), similarly to volatile anesthetics. The precise mechanism of their action on the CNS, however, is not fully understood, and remains to be clarified. This study is focused on how i...

Blood concentrations of 11 volatile organic compounds (VOCs) were measured up to four times over 2 years in a probability sample of more than 150 children from two poor, minority neighborhoods in Minneapolis, Minnesota. Blood levels of benzene, carbon tetrachloride, trichloroethene, and m-/p-xylene were comparable with those measured in selected adults from the Third National Health and Nutriti...

Molecular sieving MFI-type zeolite membranes were prepared by a secondary growth method without using an organic template. Silicalite membranes with intercrystalline pores minimized or eliminated were obtained by this synthesis method which avoids the template removal step. The silicalite membrane exhibits molecular sieving characteristics with pervaporation separation factor for p-xylene to o-...

Four pure cultures of denitrifying bacteria, which had previously been isolated on defined alkylbenzenes, were capable of anaerobic growth with crude oil as the only source of organic substrates. Chemical analyses after growth revealed that the known growth substrates toluene, ethylbenzene, and m-xylene were selectively consumed from the oil. o-Xylene and p-xylene, which as pure compounds did n...

A novel sulfate-reducing bacterium isolated from fuel-contaminated subsurface soil, strain PRTOL1, mineralizes toluene as the sole electron donor and carbon source under strictly anaerobic conditions. The mineralization of 80% of toluene carbon to CO2 was demonstrated in experiments with [ring-U-14C]toluene; 15% of toluene carbon was converted to biomass and nonvolatile metabolic by-products, p...

OBJECTIVES Ethanol may be a significant combined factor in human solvent toxicity. Lipid peroxidation has been suggested to be an important contributing mechanism involved in experimental alcohol-induced liver injury. The aim of the study was to investigate whether a short-term ethanol ingestion in rats chronically exposed to m-xylene vapor may influence the lipid peroxidation rate in the intra...

Biofiltration is an effective technology for the treatment of gaseous waste. However, a biofiltration system needs a bioreactor of large volume and it is slow to adapt to fluctuating concentrations in waste gas. To overcome these disadvantages, a bench-scale system integrating a biofilter and an adsorption unit for the treatment of gases containing o-xylene was investigated in this study. The a...