objective: cell vital function has correlation with mechanical loadings that cell experiences. here, effects of in-vitro combined cyclic-static stretch on proliferation of human mesenchymal stem cell (hmsc) were evaluated. materials and methods: hmscs were cultured on gelatin coated elastic membranes, and exposed to stretch loading. four different regimes of cyclic, static, combined cyclic-sta...

We describe a new method, called cyclic abduction, for automatically inferring safety and/or termination preconditions for heap-manipulating while programs, expressed as inductive definitions in separation logic. Cyclic abduction essentially works by searching for a cyclic proof of memory safety and/or termination, abducing definitional clauses of the precondition as necessary in order to advan...

1. A wide range of purine bases, nucleosides and cyclic nucleotides were shown to induce betacyanin synthesis in Amaranthus seedlings. 2. The induction of pigment by benzyladenine, dibutyryl cyclic AMP or cyclic AMP was not potentiated by aminophylline. Aminophylline was shown to inhibit Amaranthus cyclic AMP phosphodiesterase activity. 4. Incubation of seedlings with aminophylline inhibited th...

A cyclic renewal process is considered as an extension of an alternating renewal process, where each of the underlying independently and identically distributed (i.i.d.) nonnegative random increments is composed of multiple stages. Such a process may be appropriate for analyzing optimal preventive maintenance policies for production management, where a pair of two stages representing an uptime ...

We demonstrate a method for the synthesis of cyclic polymers and a protocol for characterizing their diffusive motion in a melt state at the single molecule level. An electrostatic self-assembly and covalent fixation (ESA-CF) process is used for the synthesis of the cyclic poly(tetrahydrofuran) (poly(THF)). The diffusive motion of individual cyclic polymer chains in a melt state is visualized u...

Based on time series gene expressions, cyclic genes can be recognized via spectral analysis and statistical periodicity detection tests. These cyclic genes are usually associated with cyclic biological processes, for example, cell cycle and circadian rhythm. The power of a scheme is practically measured by comparing the detected periodically expressed genes with experimentally verified genes pa...

Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated...

Glucagon (10 nM) caused a transient elevation of intracellular cyclic AMP concentrations, which reached a peak in around 5 min, and slowly returned to basal values in around 30 min. When 1 mM-3-isobutyl-1-methylxanthine (IBMX) was present, this process yielded a Ka of 1 nM for glucagon. The addition of insulin (10 nM) after 5 min exposure to glucagon (10 nM) caused intracellular cyclic AMP conc...