The Cyberknife represents a new, frameless stereotactic radiosurgery system which efficiently incorporates advance robotics with computerized image reconstruction to allow highly conformal image guided radiation delivery. This review focus is on the pros and cons of this new radiotherapy tool, its current indications, safety profile and future directions. A literature search of Medline, Pubmed,...

Treatment of prostate cancer with SBRT is an area of significant controversy for many in the radiation oncology community despite radiobiologic data that strongly suggest the prostate would be an excellent SBRT target. Recently, new data have emerged that show promising outcomes with minimal toxicity for CyberKnife SBRT of prostate cancer. In the following we present the motivating factors for ...

geons, neurologists, neuroradiologists, and other practitioners. The purpose of this publication is to provide these physicians with current management strategies for dealing with a variety of disorders and conditions in the neurosciences, and to provide up-to-date diagnostic and prognostic information written by specialists in the field. It is estimated that it will take the physician 1 hour t...

We present a case of malignant pleural mesothelioma with focal relapse in the Azygos arch region after radical pleurectomy/decortication and adjuvant chemotherapy. Tumour recurrence was successfully treated by Cyberknife radiosurgery (70 Gy in five fractions). Patient remains disease-free at 40 months without any other treatment.

BACKGROUND/AIMS We present the preliminary results of a cost-effectiveness analysis of cyberknife radiosurgery (CKR) versus microvascular decompression (MVD) for patients with medically unresponsive trigeminal neuralgia. METHODS Direct healthcare costs from hospital's perspective attributable to CKR and MVD were collected. Pain level caused by trigeminal neuralgia was measured through the Bar...

Single fraction radiosurgery is conventionally precluded for lesions lying <2-3 mm of the anterior visual pathway because of the radiosensitivity of the optic nerve. We analyzed a series of 64 patients with "perioptic" meningiomas treated by CyberKnife multisession radiosurgery and hypofractionated stereotactic radiotherapy (hSRT). Between July 2007-May 2010, patients were treated using convent...

Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution alon...

OBJECTIVE To determine the success rate and complication of CyberKnife Robotic Radiosurgery for treating intracranial and extra cranial tumours. METHODS The cross-sectional observational study was carried out at the Department of CyberKnife Robotic Radiosurgery at the Jinnah Postgraduate Medical Centre, Karachi, and reviewed data related to a year from December 2012 to December 2013. Patients...