background: injured phrenic nerve secondary to cardiac surgeries is the most common cause of diaphragmatic paralysis (dp) in infants. the aim of this study was to determine the risk factors for dp caused by congenital heart defect corrective surgeries in pediatrics. methods: this cross-sectional study, conducted in a 2-year period (2006 – 2008), included 451 children with congenital heart disea...

Endothelial-derived nitric oxide (NO) diffuses abluminally to regulate blood flow by activating soluble guanylate cyclase in medial smooth muscle. However, a significant fraction of NO diffuses luminally, where the extremely high reaction rate with red blood cell hemoglobin (Hb) effectively reduces luminal concentration to zero. The erythrocytosis of cyanotic congenital heart disease has potent...

AIMS Recurrent venesection of patients with cyanotic congenital heart disease may be detrimental, with an increased risk of cerebrovascular events and symptomatic iron-deficiency. The aim of this study was to determine the venesection policies as practised in hospitals within a U.K. region and to determine if these policies followed current recommendations. METHODS AND RESULTS Fifty-eight con...

Objective—To evaluate changes in cognitive and academic functioning following cardiac surgery in children with congenital heart disease. Design—A prospective cross sectional study in which patients were assessed immediately before treatment and 12 months later. Patients—Three groups of children aged 3.5–17 years: a group with congenital heart disease awaiting surgery, another awaiting bone marr...

In neonates, aneurysm of the vein of Galen often masquerades as cyanotic congenital heart disease. We report 4 cases of neonates presenting with malformation of the vein of Galen at our insititution. An increased awareness of this entity seems warranted.

©2010 UpToDate Print | Back Evaluation and initial management of cyanotic heart disease in the newborn Authors Robert L Geggel, MD Laurie B Armsby, MD Section Editors David R Fulton, MD Joseph A Garcia-Prats, MD Deputy Editor Melanie S Kim, MD Last literature review version 18.2: May 2010 | This topic last updated: May 2, 2007 (More) INTRODUCTION — Cyanotic lesions comprise approximately one-th...