background: cutaneous leishmaniasis is a neglected parasitic disease, which imposes massive human distress and financial costs to the endemic countries. better understanding of host immune response to the parasite leads to helpful strategies for disease control. interleukin (il)-10 and transforming growth factor (tgf)-β are important immune regulatory cytokines, which appear to develop non-heal...

background: leishmaniasis is a zoonotic disease caused by species of protozoa of the genus leishmania . in recent years, incidence of cutaneous leishmaniasis has increasing trend in golestan province, north of iran. the aim of the present study was to identify the frequency of cutaneous leishmaniasis using pcr-rflp in patients referred to kalaleh health center, during 2013-14. methods: this des...

cutaneous hodgkin’s lymphoma is a rare disease (0.5% to 3.4%) which tends to be in the setting of an advanced disease and has a poor prognosis. treatment of patients with cutaneous involvement of hodgkin’s lymphoma is according to dissemination of disease (systemic or localized therapy). the majority of data in this context are based on individual case reports or literature reviews. we have rep...

a uterocutaneous fistula is a rare clinical presentation that occurs following cesarean section and other pelvic operations. there are only a few reports discussing the treatments. we describe a patient with successful surgical management and review the literature. a 25-year-old woman referred to our department 13 months after her first cesarean section. she had a history of an abdominal mass a...

introduction: this study was done to compare the efficacy of interlesional injection of glucantime method and cryotherapy with interlesional injection in treatment of cutaneous leishmaniasis in qom province. methods: in this randomized controlled trial patients were randomly allocated in the two arms of the study:one receiving interalesional glucantime injection weekly and the other receiving b...

background: cutaneous leishmaniasis (cl) is a major health problem in many parts of iran, although diagnosis of cl especially in the endemic area is easy, but treatment and management of the disease is a global dilemma. diag-nosis of cl in non-endemic area is not as simple as in endemic foci. in this study, the status and the proportions of cl induced by leishmania major and l. tropica among cl...

due to the epidemiological alteration in distribution of candida species as well as significant increasing trend of either intrinsic or acquired in resistance of some of these fungi, the precise identification of candida species is necessary for effective antifungal therapy and also for prevention of nosocomial infections. pcr-rflp method is indicated to be a reliable, rapid and simple techniqu...

conclusions according to the current study results, it may be concluded that ethanol extract of p. harmala is efficient in the treatment of cutaneous leishmaniasis, and the efficiency is comparable with that of glucantime. results the results showed that ethanol extract of p. harmala had good therapeutic efficacy in treatment of lesions in mice (p < 0.05), and the efficacy was significant in th...

results fifty four of 84 (64.2%) slides obtained from patients had positive results microscopically, while 79/84 (94%) of slides had positive results by fta card-nested-pcr. pcr and microscopy showed a sensitivity of 96.4% and 64.2% and specificity of 100% and 100%, respectively. interestingly, leishmania major as causative agent of zoonotic cl was identified in 100% and 90.7% of cl cases from ...

b a ckground: the objective of this study was to assess the epidemiological characteristics of a new emerging focus of cutaneous leishmaniasis (cl) in southern villages of bam district, southeastern iran, 2010. m e t hods: a house-to- house census survey of 5544 individuals were interviewed and physically examined for the presence of active lesions or scars. diagnosis was confirmed by direct sm...