Erythema dyschromicum perstans (EDP) and Lichen planus pigmentosus (LPP) are both inflammatory disorders of pigmentation with unknown etiology difficult to differentiate clinically histologicaly. There is no consensus on whether entities separate or belong the same spectrum cutaneous disorders. We present a 13 year old boy mostly asymptomatic hyperpigmented lesions over body. The were subsequen...

A 43-year-old man with generalized lichen planus demonstrated serum antibodies against autologous lesional skin. Indirect immunofluorescence using serum and papular lesional skin revealed a lichen planus specific antigen found only in the granular layer. The specific tissue antigen was not detected in normal skin from this patient, in normal skin from patients with skin disorders other than lic...

Ulcerative lichen planus of the feet is a rare variant of lichen planus. We report a case presenting with chronic painful ulceration of the feet and cicatricial changes of the toenails. The pathology of the ulceration showed diagnostic of lichen planus. She also had typical lichen planus on the dorsal hands. The ulceration was resistant to many kinds of topical agents, but completely healed wit...

© 2016 The Authors. doi: 10.2340/00015555-2169 Journal Compilation © 2016 Acta Dermato-Venereologica. ISSN 0001-5555 Paraneoplastic pemphigus (PNP), described in 1990 by Anhalt et al. (1), is an autoimmune mucocutaneous blistering disease characterized by severe mucosal erosions and polymorphic cutaneous lesions. In 2001 the term paraneoplastic autoimmune multi-organ syndrome (PAMS) was coined ...

Sir, Interferons (IFNs) are cytokines widely used in medicine for their antiproliferative, antiviral and immunomodulatory effects. Their most common side effect is an in ̄uenza-like syndrome characterized by fever, headache and muscle pain. Also, IFNs infrequently induce or worsen some dermatoses, such as herpes labialis, psoriasis, pemphigus and vitiligo (1). Several papers have referred to the...

This article describes 31 examples of acantholytic acanthoma, a newly recognized, solitary, benign cutaneous tumor. Acantholytic acanthoma was typically an asymptomatic, keratotic papule or nodule. Patients ranged in age from 32 to 87 years (median 60 years); the ratio of men to women was 2:1; the most frequent clinical diagnosis was keratosis; and half of the growths were on the trunk of the b...

Lichen planus is an uncommon disease in children, and only 2 to 3% of affected patients are under twenty years of age. This dermatosis may appear in several clinical forms, which vary according to the morphology and distribution of lesions. In less than 0.2% of all lichen planus cases, the lesions are distributed along the lines of Blaschko, and is a variant called linear lichen planus. This is...

References 1. Daoud MS, Pittelkow MR. Lichen planus. In: Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, Wolff K, editors. Fitzpatrick’s Dermatology in General Medicine. 8th ed. New York: McGraw-Hill; 2012. p. 296-312. 2. Weedon D. Weedon’s Skin Pathology. 3rd ed. London: Churchill Livingstone Elsevier; 2010. 3. Hanau D, Sengel D. Perforating lichen planus. J Cutan Pathol 1984;11:17...

PURPOSE To describe a case of cicatricial keratoconjunctivitis associated with lichen planus. METHODS Case report. RESULTS To our knowledge, this is the sixth reported case of cicatricial keratoconjunctivitis associated with lichen planus. A 73-year-old woman had persistent cicatricial keratoconjunctivitis. Histopathologic studies of the buccal mucosa biopsy specimen revealed lichen planus....