This study looks at blood flow in four different human right coronary arteries (RCAs), which have been reconstructed from bi-plane angiograms. A generalized power-law model of blood viscosity is used to study the blood flow at a particular point in the cardiac cycle. Large differences are found in the wall shear stress magnitude (WSS) distributions in the four arteries, leading to the conclusio...

The present work aims at optimizing the geometry of curved trapezoidal winglets to enhance heat transfer rates (expressed as Colburn factor, j) and minimize pressure losses friction f). A fin-and-tube exchanger was analyzed with mounted on alternate tube either side fins. Multi-objective optimization performed using genetic algorithm (GA) maximize j f. Two surrogate models, viz. response surfac...

OBJECTIVE We applied optical flow method (OFM) to quantify relative velocities of blood flow using digital subtraction angiography (DSA) in the vascular analysis of hepatocellular carcinoma (HCC) patients who underwent transarterial chemoembolization (TACE) treatment. METHODS A total of 40 HCC patients treated by TACE were analyzed in this study. DSA imaging with a 12-inch field of view, 1024...

In a curved tube, the amount of airflow appears to be influenced by the amount of curvature. The purpose of this study was to investigate changes in obstructive sleep apnoea (OSA) severity and awake velopharyngeal curvature in response to an anteriorly titrated mandibular position in 20 male OSA patients. Baseline supine cephalometry was obtained before the initial insertion of a titratable ora...

constant communication with an intelligence analyst at operations command, and receives orders through an earpiece to don chemical-protection equipment because of new chemical weapons threat intelligence in the area. The chemical-protection suit is similar to but weighs less than those in use today. Most importantly, because it encloses the soldier's head, the suit has an augmented hearing syst...

Mitochondrial cytochrome P450 11A1 (CYP11A1 or P450 11A1) is the only known enzyme that cleaves the side chain of cholesterol, yielding pregnenolone, the precursor of all steroid hormones. Pregnenolone is formed via three sequential monooxygenation reactions that involve the progressive production of 22R-hydroxycholesterol (22HC) and 20α,22R-dihydroxycholesterol, followed by the cleavage of the...

BAR domain proteins contribute to membrane deformation in diverse cellular processes. The inverted-BAR (I-BAR) protein IRSp53, for instance, is found on the inner leaflet of the tubular membrane of filopodia; however its role in the formation of these structures is incompletely understood. Here we develop an original assay in which proteins are encapsulated in giant unilamellar vesicles connect...

One-lung anesthesia was performed first by Gale and Waters in 1932.' They devised a curved, singlelumen cuffed tube which could be passed blindly into either mainstem bronchus.2 This accomplishment spurred the evolution of a variety of endobronchial tubes for one-lung anesthesia over the following years. One-lung anesthesia has been utilized for thoracic surgery for several decades. The lateral...