OBJECTIVE This study aimed to examine the efficacy and safety of nepafenac ophthalmic suspension compared to placebo in the management of postoperative inflammation and ocular pain in Japanese patients undergoing cataract surgery. METHODS This was a multicenter, randomized, double-masked, placebo-controlled clinical study. Patients received nepafenac or placebo TID beginning 1 day before cata...

BACKGROUND Although mucosal leishmaniasis is a prominent disease, it has been studied only to a limited extent. It is classically treated with parenteral antimony or, as a last resort, amphotericin B. METHODS We treated Bolivian mucosal leishmaniasis due to Leishmania braziliensis with the oral agent miltefosine, 2.5 mg/kg/day for 28 days, and followed-up for 12 months. RESULTS Seventy-two ...

results two major themes were extracted from the analysis of the transcripts: “comprehensive caring commitment” and “patients’ medication grudge”. conclusions according to the findings, the nurses are in a unique position to care for people with ms; therefore they should be ready to provide high-quality patient care in ms patients. patients must be encouraged to study about their condition and ...

OBJECTIVE To assess the potential of integrating malaria control interventions in underused health services. METHODS Using the Piot predictive model, we estimated malaria cure rates by deriving parameters influencing treatment at home and in health facilities from the best-performing African malaria programmes and applying them to Yanfolila district, Mali. RESULTS Without any malaria contro...

A prospective, non-randomized, open clinical trial was conducted to determine the efficacy of itraconazole for treatment of Microsporum ferrugineum tinea capitis. Itraconazole capsules were given every day in continuous group and every day for 1 week on and 3-week off in pulse therapy group. Concomitant topical therapy with 2% ketoconazole shampoo was used daily. Clinical evaluation consisted o...

1. A.B.Shetty Memorial Institute of Dental Sciences Nitte University, Deralakatte, Mangalore, Karnataka, India. 2. Mangalore University, Karnataka, India. Abstract : Cure rate models are survival models consisting of a cured fraction and an uncured fraction. These models are being widely used in analyzing data from cancer clinical trials. A model to estimate the cure fraction was first develope...