Reduced host cell reactivation (HCR) of a reporter gene containing 8-oxoguanine (8-oxoG) lesions in Cockayne syndrome (CS) fibroblasts has previously been attributed to increased 8-oxoG-mediated inhibition of transcription resulting from a deficiency in repair. This interpretation has been challenged by a report suggesting reduced expression from an 8-oxoG containing reporter gene occurs in all...

Modern nucleon-nucleon (NN) potentials, which accurately fit the nucleon-nucleon scattering phase shifts, contain terms which break isospin symmetry. The effects of these symmetry violating terms on the bulk properties of nuclear matter are investigated. The predictions of the charge symmetry breaking (CSB) terms are compared with the Nolen-Schiffer (NS) anomaly regarding the energies of neighb...

BACKGROUND Cheyne Stokes Breathing (CSB), a form of central sleep apnea is often found in medical illnesses such as heart failure, stroke or renal failure. Adaptive servo-ventilation (ASV) has been reported to be an effective treatment of CSB in heart failure. However, there are no reports about using ASV for idiopathic CSB, which is not associated with heart failure or other serious medical pr...

Compulsive sexual behaviour (CSB) is relatively common and has been associated with significant distress and psychosocial impairments. CSB has been conceptualized as either an impulse control disorder or a non-substance 'behavioural' addiction. Substance use disorders are commonly associated with attentional biases to drug cues which are believed to reflect processes of incentive salience. Here...

The Internet provides a large source of novel and rewarding stimuli, particularly with respect to sexually explicit materials. Novelty-seeking and cue-conditioning are fundamental processes underlying preference and approach behaviors implicated in disorders of addiction. Here we examine these processes in individuals with compulsive sexual behaviors (CSB), hypothesizing a greater preference fo...

UNLABELLED BACKGROUND AND AIMS :Compulsive sexual behavior (CSB) is a common behavior affecting 3-6% of the population, characterized by repetitive and intrusive sexual urges or behaviors that typically cause negative social and emotional consequences. METHODS For this small pilot study on neurological data, we compared 13 individuals with CSB and gender- matched healthy controls on diagnosti...

Chiral effective field theory predicts a charge symmetry violating (CSB) amplitude for pion-nucleon scattering. This mechanism provides a very large contribution also to the CSB forward-backward asymmetry in the angular distribution of the reaction pn → dπ. This contribution was so large that it had a potential to cause a large effect also in CSB elastic NN scattering and to disturb its present...

Introduction: During the neonatal period, metabolism of bilirubin is in transition from the fetal stage to the adult stage1. Uridine diphosphoglucuronyl transferase (UDPGT), an important liver enzyme for conjugation and excretion of bilirubin, is detectable at 18 – 20 weeks of gestation. UDPGT levels in full term neonates are usually less than 0.1% of adult values. Adult value of this enzyme ac...

The objective of this study was to evaluate, within the context of a randomized controlled trial of product effectiveness, the acceptability of new formulations of six corn-soy blended flours (CSB) and six lipid-based nutrient supplements (LNS) with different quantities of milk and qualities of soy for the treatment of children with moderate acute malnutrition (MAM). Our study included 1546 chi...

We aimed to investigate the association between genetic variants of the DNA repair genes XPG, CSB, XPC, CCNH, and MMS19L in the nucleotide excision repair (NER) pathway and risk of prostate cancer in a population in China. This study included 229 patients with newly diagnosed and histopathologically confirmed primary prostate cancer and 238 healthy controls. Genotyping of XPG, CSB, XPC, CCNH, a...