Patients with inflammatory bowel disease (IBD) and bowel resection might experience reduced effectiveness from oral contraceptive agents. We report a case of a woman with Crohn disease who became pregnant while compliant with her combined oral contraceptive pill (OCP) regimen. Patients with Crohn disease have a greater risk of contraceptive failure because the diseased bowel causes increased pa...

C rohn’s disease (CD) and ulcerative colitis result from an inappropriate response of the mucosal immune system to the normal enteric flora in a genetically susceptible individual. The importance of genetic predisposition was firmly established in 2001 by the identification of the first CD susceptibility gene NOD2 (CARD15) on chromosome 16q12 (IBD1). 2 It is now clear that NOD2 variants contrib...

the factors such as disease can disrupt homeostasis, resulting in perturbations of endogenous biochemicals that are involved in key metabolic profiles. metabonomics is useful technique to quantitative description of endogenous metabolites present in a biological sample such as urine, plasma and tissue. high resolution 1 h nuclear magnetic resonance (nmr)-based metabonomics is a technique used t...

In Crohn disease, bowel-preserving surgery is necessary to prevent short bowel syndrome due to repeated operations. This study aimed to determine the remnant small bowel length cut-off and to evaluate the clinical factors related to nutritional status after small bowel resection in Crohn disease.We included 394 patients (69.3% male) who underwent small bowel resection for Crohn disease between ...

Definition Typical presentation of Crohn disease includes inflammation in the terminal ileum. However, this typical presentation with ileitis is seen only in 70% of cases. 25% of patients present with disease confined only to the colon (Crohn colitis) and in 5% exclusive involvement of the upper gastrointestinal tract is seen. The diagnosis is mostly based on a suggestive clinical course, a typ...

OBJECTIVE The purpose of this article is to review MR enterography technique and imaging findings suggestive of Crohn disease on these examinations. This article will also allow the reader to self-assess and improve his or her skills in the performance and interpretation of MR enterography examinations. CONCLUSION This article reviews the technique of performing MR enterography examinations. ...

Careful examination of the oral cavity may reveal findings indicative of an underlying systemic condition, and allow for early diagnosis and treatment. Examination should include evaluation for mucosal changes, periodontal inflammation and bleeding, and general condition of the teeth. Oral findings of anemia may include mucosal pallor, atrophic glossitis, and candidiasis. Oral ulceration may be...

Pellagra is a nutritional disease caused by the deficiency of niacin. We describe a case of pellagra as the initial presentation of Crohn disease, which has been rarely described in the literature.

BACKGROUND Two-thirds to three-fourths of patients with either refractory luminal or fistulizing Crohn disease respond to infliximab treatment. The ability or inability to respond seems to persist over time. Biological characteristics and/or genetic background can influence the response to treatment. The aim was to assess the value of C-reactive protein and TNF-alpha serum levels before treatme...

We propose here the main characteristics of 'Ileibacterium massiliense' strain Marseille-P3115, which was isolated from the ileum liquid sample of a patient with Crohn disease.