This Viewpoint paper has grown out of a presentation at the American College of Medical Informatics 2007 Winter Symposium, the resulting discussion, and several activities that have coalesced around an issue that most informaticians accept as true but is not commonly considered during the implementation of Electronic Health Records (EHR) outside of academia or research institutions. Successful ...

De novo expression of Muc5ac, a mucin not normally expressed in the intestinal tract, is induced in the cecum of mice resistant to Trichuris muris infection. In this study, we investigated the role of Muc5ac, which is detected shortly before worm expulsion and is associated with the production of interleukin-13 (IL-13), in resistance to this nematode. Muc5ac-deficient mice were incapable of exp...

Realistic equations of state valid in the whole state space of a multi-component mixture should satisfy at least three important constraints: (i) The Gibbs phase rule holds. (ii) At low densities, one can deduce a virial equation of state with the correct multicomponent structure. (iii) Close to critical points, plait points, and consolute points, the correct universality and scaling behavior i...

Faculty in a twenty-first century school of dentistry face a variety of daily challenges. Balancing teaching, research, and scholarship can be an overwhelming task for junior faculty and is influenced by the environment and the interactions we have with colleagues. Effective mentorship can play a critical role in professional growth and development as well as academic success. Excellent mentors...

The last decade has shown that object-oriented concept by itself is not that powerful to cope with the rapidly changing requirements of ongoing applications. Component-based systems achieve flexibility by clearly separating the stable parts of systems (i.e. the components) from the specification of their composition. In order to realize the reuse of components effectively in CBSD, it is require...

Microevolution is typically ignored as a factor directly affecting ongoing population dynamics. We show here that density-dependent natural selection has a direct and measurable effect on a planktonic predator-prey interaction. We kept populations of Brachionus calyciflorus, a monogonont rotifer that exhibits cyclical parthenogenesis, in continuous flow-through cultures (chemostats) for more th...

Commercial-Off-The-Shelf (COTS) software components are being used within complex safety-critical applications. However, to use them with confidence, it is necessary to ensure that potential failures of the COTS component does not contribute to system level hazards. To this end, we have established a contract-based approach to capture the application-specific safety requirements, and correspond...

Objects are often identified by the shape of their contours. In this study, visual search tasks were used to reveal a visual dimension critical to the analysis of the shape of a boundary-defined area. Points of maximum curvature on closed paths are important for shape coding and it was shown here that target patterns are readily identified among distractors if the angle subtended by adjacent cu...

The present empirical study investigates, analyzes, and discusses the affordances limitations of an augmented reality (AR)-based educational intervention for critical digital awareness secondary school students through a sociocultural framework instruction. design focuses on empowerment students’ skills in new media produsage ecosystem parallel with development target language content integrate...