Several alkaloids with anticancer activities have been reported among the Crinum species. In this study, an in silico screening of crinine was carried out to identify potential Caspase-3 activators and anti-angiogenic compounds. Thirty-one (31) were assessed for drug-likeness using SwissADME online Web server. Nine (9) alkaloids, satisfying Lipinski’s rules selected screened cytotoxic propertie...

This study determined the most effective of three doses per plant extract on L3 nematode larvae. Seven plant species: Crinum macowanii, Gunnera perpensa, Nicotiana tabacum, Sarcostema viminale, Vernonia amygdalina, Zingiber officinale and Zizyphus mucronata, had alkaloids and tannins as bioactive principle. Ovendried leaf samples (40 g; 20 g; 10 g) of each species were extracted in 70% ethanol,...