The instability of Hoogsteen base pairs relative to Watson-Crick base pairs has limited biological applications of triplex-forming oligonucleotides. Hydrated ionic liquids (ILs) provide favourable environments for a wide range of chemical reactions and are known to impact the stabilities of Watson-Crick base pairs. We found that DNA triplex formation was significantly stabilized in hydrated cho...

The Framework Recently Crick and Koch offered a " Framework for Consciousness " (2003). Pradeep Mutalik's review of that article in SCR (Mutalik 2003) asserts that " Crick and Koch describe ten aspects of a framework that they believe offers a coherent scheme for explaining the neural correlates of consciousness. " Crick and Koch explain that a framework must not be confused with a set of hypot...

The phenomenon known as Watson-Crick complementarity is basic both in the experiments and theory of DNA computing. While the massive parallelism of DNA strands makes exhaustive searches possible, complementarity constitutes a powerful computational tool. It is also very fruitful to view complementarity as a language-theoretic operation: \bad" words obtained through a generative process are repl...

Abstract Watson-Crick L systems are string generating formal models obtained by augmenting Lindenmayer with the morphism inspired complementarity principle. The is controlled a trigger —a boolean condition eventually met generated word. Despite their simplicity, (D)0 have interesting mathematical properties, strong generative power, and they can also characterize some open decision problems. Fu...

Several crystal structures of RNA fragments, alone or in complex with a specific protein, have been recently solved. In addition, the structures of an artificial ribozyme, the leadzyme, and the cleavage product of a human pathogen ribozyme, have extended the structural diversity of ribozyme architectures. The attained set of folding rules and motifs expand the repertoire seen previously in tRNA...