نتایج جستجو برای: creb3 protein

تعداد نتایج: 1234699  

Journal: :avicenna journal of medical biotechnology 0

background: fragile histidine triad protein (fhit), as a known tumor suppressor protein, has been proposed to play crucial role in inhibiting p53 degradation by mdm2. studies have confirmed fhit interaction with p53 or mdm2, although functional interacting domains of fhit with mdm2 and/or p53 are not completely defined. thus, through determining the significant structural interacting domains of...

Journal: :medical journal of islamic republic of iran 0
massoud boojar from the institute of biochemistry and biophysics, university of tehran, tehran, islamic republic of iran. azra rabbani

we have investigated the effect of theophylline on the kinetics of the catalytic subunit of protein kinase and related factors in lung tissue. the results show that the point of highest concentration of the c subunit of protein kinase which is active in casein phosphorylation is at 3h of incubation time, but in the presence of 100 ilg/ inl and 10µg/ml theophylline, this is shifted to i.s and 2....

Journal: :reports of biochemistry and molecular biology 0
farzad khademi antimicrobial resistance research center, department of medical bacteriology and virology, qaem university hospital, school of medicine, mashhad university of medical sciences, mashhad, iran. arshid yousefi-avarvand antimicrobial resistance research center, department of medical bacteriology and virology, qaem university hospital, school of medicine, mashhad university of medical sciences, mashhad, iran. mohammad derakhshan antimicrobial resistance research center, department of medical bacteriology and virology, qaem university hospital, school of medicine, mashhad university of medical sciences, mashhad, iran. zahra meshkat antimicrobial resistance research center, department of medical bacteriology and virology, qaem university hospital, school of medicine, mashhad university of medical sciences, mashhad, iran. mohsen tafaghodi nanotechnology research center, school of pharmacy, mashhad university of medical sciences, mashhad, iran. kiarash ghazvini antimicrobial resistance research center, department of medical bacteriology and virology, qaem university hospital, school of medicine, mashhad university of medical sciences, mashhad, iran.

background: the purpose of this study was to clone, express, and purify a novel multidomain fusion protein of micobacterium tuberculosis (mtb) in a prokaryotic system. methods: an hspx/esxs gene construct was synthesized and ligated into a pgh plasmid, e. coli top10 cells were transformed, and the vector was purified. the vector containing the construct and pet-21b (+) plasmid were digested wit...

2016
Hao Xue Guang Yuan Xing Guo Qinglin Liu Jinsen Zhang Xiao Gao Xiaofan Guo Shugang Xu Tong Li Qianqian Shao Shaofeng Yan Gang Li

Hypoxia induces protective autophagy in glioblastoma cells and new therapeutic avenues that target this process may improve the outcome for glioblastoma patients. Recent studies have suggested that the autophagic process is upregulated in glioblastomas in response to extensive hypoxia. Hypoxia also induces the upregulation of a specific set of proteins and microRNAs (miRNAs) in a variety of cel...

Journal: :journal of biotechnology and health sciences 0
samiie pouragahi department of molecular medicine, school of medicine, qazvin university of medical sciences, qazvin, ir iran; department of bioinformatics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran; department of pharmacology, cellular and molecular research center, school of medicine, qazvin university of medical sciences, qazvin, ir iran mohammad hossein sanati department of molecular genetics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran mehdi sadeghi department of bioinformatics, national institute of genetic engineering and biotechnology (nigeb), tehran, ir iran marjan nassiri-asl department of pharmacology, cellular and molecular research center, school of medicine, qazvin university of medical sciences, qazvin, ir iran; school of medicine, qazvin university of medical sciences, qazvin, ir iran. tel: +98-2833336001, fax: +98-2833324971

conclusions the growth rate of information in bioinformatics databases could facilitate studies of live organisms prior to observation studies. two different protein classes could be causative agents of one disease. however, two related diseases from one disease group could consist of different protein classes. future research in the field of proteomics could allow modern insight to reshuffling...

Journal: :iranian biomedical journal 0
محسن ابولحسنی mohsen abolhassani

antiproliferative protein (app) isolated from conditioned media of two androgen-independent prostatic carcinoma cell lines, pc3 and du-145 was shown to inhibit selectively cell proliferation of androgen-dependent prostate cancer cell line lncap in a dose dependent manner. this protein was further purified with hplc using hydrophobic interaction column (phenyl 5pw) and was used to study the modu...

Journal: :iranian journal of blood and cancer 0
mohammad pedram bijan keikhaei afshin fathi firoozeh dehyouri

background: sickle cell disease occurs due to a mutation in β chains and the substitution of valine instead of glutamate in the sixth position of the ß-chain that causes polymerization and vascular blockage. the aim of this study was to compare the serum c, s proteins and factor v leiden between sickle cell patients and the control group. materials and methods: in this case-control study, perfo...

Journal: :iranian journal of applied animal science 2015
m.h. sekhavati m. tahmoorespur t. abbassi-daloii s. yousefi a.a. khabiri

there are two different co-expression systems including bicistronic; dual-vector or two-promoter to express two different genes simultaneously and also to study protein-protein interactions. bicistronic system has disadvantages e.g. compared with two-promoter system. in this paper, a simple method based on spliced overlap extension by polymerase chain reaction (soe-pcr) technique was demonstrat...

Journal: :jentashapir journal of health research 0
mahboubeh baheri biology department, shahid chamran university of ahvaz, ahvaz, ir iran mohammad reza dayer biology department, shahid chamran university of ahvaz, ahvaz, ir iran; biology department, shahid chamran university of ahvaz, ahvaz, ir iran

conclusions accordingly, it can be concluded that locally low temperatures and acidic conditions are the main suspected reasons for protein misfolding. results based on the study findings the low temperature, 0°c, and acidic condition change the structure more strongly than other mentioned conditions. the low temperature and acidic conditions seem to have the most misfolding effect on insulin s...

Journal: :jundishapur journal of microbiology 0
fatemeh fotouhi influenza research lab, department of virology, pasteur institute of iran, tehran, ir iran; influenza research lab, department of virology, pasteur institute of iran, , tehran, ir iran.tel/ fax: +98-2166496517 behrokh farahmand influenza research lab, department of virology, pasteur institute of iran, tehran, ir iran behnaz heidarchi influenza research lab, department of virology, pasteur institute of iran, tehran, ir iran maryam esghaei virology department, iran university of medical sciences, tehran, ir iran sima rafati molecular immunology and vaccine research lab, department of immunology, pasteur institute of iran, tehran, ir iran masoumeh tavassoti kheiri influenza research lab, department of virology, pasteur institute of iran, tehran, ir iran

background permanent antigenic variation of influenza viruses causes a major concern to develop an effective human influenza vaccine. conserved antigens are new vaccine candidates because it is not necessary to match the prepared vaccine with circulating strains. ion channel m2 protein is conserved among all influenza a viruses, allowing the virus to enter host cells. objectives to prepare an e...

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