background: hypertension is one the most common causes of chronic kidney disease (ckd). one of the major concerns in hypertensive patients is early detection of renal disorders. in the past, serum creatinine (scr) concentration was used as a marker of kidney function, but it proffers a late reflection of reduced glomerular filtration rate. cystatin c and neutrophil gelatinase-associated lipocal...

purpose post exercise proteinuria and increased urinary gamma-glutamyl transferase (ggt) levels can be indicative of exercise-induced renal damage. the aim of this investigation is to study the effect of one session of intensive training on renal damage markers and compare their values to those 6 hours after training. methods in this cross-sectional study with pre- and post-test design, 10 elit...

this study evaluates the effect of preoperative increased level of serum creatinine (cr) on early outcomes after coronary artery bypass graft surgery (cabg). 1140 patients who underwent cabg in our center were studied. patients with cr >2.25 mg/dl or preoperative dialysis and who had off-pump operations were excluded. group 1 consisted of 892 patients with normal cr (0.5-1.2 mg/dl) and group 2 ...

objective(s):bradykinin is a part of the kinin-kallikreinsystem which is involved in ischemia-reperfusion injury via b1 and b2 receptors.noscapine is a non-competitive antagonist of bradykinin receptors. noscapine has been reported to to be able to protect some organs against ischemia-reperfusion injury but its effect on renal ischemia-reperfusion injury (rir) in rats is unknown. therefore, the...

The goal of this review is to present a comprehensive survey of the many intriguing facets of creatine (Cr) and creatinine metabolism, encompassing the pathways and regulation of Cr biosynthesis and degradation, species and tissue distribution of the enzymes and metabolites involved, and of the inherent implications for physiology and human pathology. Very recently, a series of new discoveries ...

Objective- To compare the effects of xylazine-ketamine and xylazine-thiopental on cardiac rhythm indogs.Design- Experimental study.Animals- 15 mixed-bred, adult dogs of either sex.Procedures- Following premedication with xylazine HCI, either ketarnine HCI or sodium thiopentalwere administered to dogs. Cardiac rhythm was evaluated before as well as 15,30,45, and 60 minutes and3 days after induct...

Plasma urea and creatinine concentrations and urea and creatinine clearances and excretion were measured in a sample of 40 infants of 25*5-33 weeks' gestation, birth weight 720-2000 g, between the ages of 0 5 and 33 days. Creatinine excretion rate was between 60 and 120 gmol/kg/day in the first five postnatal weeks (mean 90.5) and was independent of sex or growth retardation. This can be used i...

to evaluate the value of random urinary protein creatinine ratio in prediction of 24h proteinuria in hypertensive pregnancies. method: random urine samples and routine 24h urine collections were collected from hypertensive pregnant women (n=100). reliability of random urinary protein-creatinine ratio was assessed by receiver operator characteristic (roc) curve to detect significant proteinuria ...

objective: diabetic nephropathy is a major diabetes complication. arterial resistance index (ri) may predict deterioration in kidney function. this study was designed to compare renal arterial ri in different stages of renal function according to glomerular filtration rate (gfr), serum creatinine level and proteinuria. materials and methods: in a cross-sectional study on 81 diabetic patients in...

The study aimed to evaluate the beneficial effect of platelets rich plasma (PRP) on wound heal in rabbit.Eighteen healthy male adult rabbit were used they randomly divided into two equal groups (controlgroup 9, treated group 9). Under aseptic technique 3 cm skin incision was made back (dorsal) ofanimal by scalpel, after that sutured immediately silk suture materials 0.2 USP usedsimple interrupt...