The antigenic and physical properties of several representative invertebrate phosphagen kinases have been examined in order to further characterize the relationship between taxonomic assignment, quaternary protein structure and evolution of this class of enzymes. Antibodies against dimeric arginine kinase from the sea cucumber cross-reacted with dimeric arginine kinase purified from sea urchin ...

Objective(s): Diazinon (DZ) is an organophosphate pesticide that induces oxidative damage in different organs. The aim of this study was to compare the effectiveness of nanomicelles containing curcuminoids (NCUR) and natural curcumin (CUR) in attenuating the oxidative damage induced by DZ in male rats. Materials and Methods: After a single intraperitoneal (IP) injection of DZ (100 mg/kg), the r...

As is well recognized, activities of creatine kinase (CK, EC 2.7.3.2) and lactate dehydrogenase (EC 1.1.1.27) in plasma may be substantially increased in hypothyroidism. We emphasize here that an increase and decrease in CK-MB isoenzyme, characteristic of acute myocardial infarction, can occur in hypothermic myxedema coma without myocardial infarction.

A 50-year-old woman with metastatic rhabdomyosarcoma of the ovary had increased activities of creatine kinase (CK; EC 2.7.3.2), CK-MB isoenzyme, lactate dehydrogenase (LD; EC 1.1.1.27), and LD-2 isoenzyme in her serum. The isoenzyme activities did not show a pattern of increasing, then decreasing. Clinical findings, including electrocardiograms, did not support the diagnosis of myocardial infar...

Despite the above caveat, the impressive new technology described by Gupta et al1 in this issue of Circulation: Cardiovascular Imaging should help to resolve a number of issues relative to the hypothesis that the failing heart is energy starved and that depressed high-energy phosphate flux through the creatine kinase (CK) system is a causative factor.2,3 It will allow longitudinal measurements ...

Özet– Alerjik semptomların miyokart iskemisi semptomlarına eşlik etmesi Kounis sendromu olarak tanımlanır. Etofenamat sık olarak kullanılan güvenli ve etkin bir steroid olmayan antienflamatuvar ilaçtır. Bu yazıda Kounis sendromlu 71 yaşında erkek hasta sunuldu. İntramüsküler 1 gram etofenamat enjeksiyonu sonrası eritamatöz döküntüler, kaşıntı, bulantı ve kusma, baş dönmesi, terleme ve göğüs ağr...

The prevalence of circulating macromolecular creatine kinase type 1 (macro CK type 1 or CK-immunoglobulin complexes) is significantly higher in a patient population selected for CK isoenzyme assay than in age- and sex-matched blood donors (n = 1304). In greater than 8000 patients studied, 49 individuals with macro CK type 1 were identified, yielding an overall prevalence of 0.61%. Macro CK type...

In 1991, 246 and 136 Ontario laboratories performed total creatine kinase (CK; EC 2.7.3.2) and creatine kinase-2 (CK-2) assays, respectively. A questionnaire mailed to these laboratories requested information about the types of assay used, the origin of their reference ranges, and the source of their instruments and reagents. All laboratories used current test formulations for CK, although seve...

(b) by adding antiserum to the B sub-unit of CK to a portion of a patient's sample and the control, then electro-phoresing the untreated and treated aliquots in adjacent positions on the same agarose film. On inspecting the films before enzyme substrate was added, we would see fluorescent bands cathodal and anodal, adjacent to but distinct from the position where the BB isoenzyme would be expec...

Objective: The present study evaluated the acceptance among parents of newborns to creatine kinase (CK) test in neonatal screening Duchenne Muscular Dystrophy-DMD and raised possible barriers elements that facilitate test. Methods: assessment CK for DMD was carried out through interviews, guided by a semi-structured script, with state Mato Grosso, Brazil. Results: Six hundred four participated ...