The use of methanesulfonic acid as a Brønsted acid for direct ortho-acylation of phenols and naphthols proves to be a convenient, more general and direct route to various hydroxyaryl ketones. The route is regioselective, leading to ortho C-acylated products in satisfactory to high yields in most cases. The solvent free reactions described below exhibited environmentally benign in terms of faste...

Abstract The synthesis of Lipoxin B 4 analogs (LXB ) to gain access stabilized inflammation resolving compounds is an actual field research. Focusing on variation and stabilization the conjugated E,Z,E,E C6–C13 tetraene moiety natural LXB , a methylene bridge introduced between C6 C11 suppresses any Z/E isomerization C8–C9 olefin. Intending enable prospective structure variations in connection ...

The Friedel-Crafts acylation of furan to produce 2-acyl by using acetic anhydride is industrially important but it uses highly polluting liquid acids as catalysts. In this study, supported modified heteropoly were used heterogeneous catalysts in a solventless green process. Metal exchanged dodecatungstophosphoric acid (DTP) was loaded on three different supports, and its effect evaluated. 20% w...