JOSEPH F. Ross, M.D., Editor

JOSEPH F. Ross, M.D., Editor

background: the aim of this study is to evaluate the association between different treatments and survival time of breast cancer patients using either standard cox model or stratified cox model. methods: the study was conducted on 15830 women diagnosed with breast cancer in british columbia, canada.  they were divided into eight groups according to patients’ ages and stage of disease either cox...

We describe a full maximum-likelihood fitting method of the popular single-factor Vasicek and Cox–Ingersoll–Ross models and carry this out for term-structure data from the UK and US. This method contrasts with the usual practice of performing a day-by-day fit. We also compare the results with some more crude econometric analyses on the same data sets. © 2000 Elsevier Science B.V. All rights res...

JOSEPH F. Ross, M.D., Editor

Mixed reflux of the gastroduodenal contents induces the esophageal mucosal damage and inflammation progressing chronic esophagitis and premalignant Barrett's esophagus (BE). The role of cyclooxygenase-2 (COX-2) and chronic inflammation in the progression of BE toward adenocarcinoma of the esophagus has not been extensively studied in experimental models of BE in animals and in human subjects. W...

It is estimated that underlying infections and inflammatory responses are linked to 15-20% of all deaths from cancer worldwide. Inflammation is a physiologic process in response to tissue damage resulting from microbial pathogen infection, chemical irritation, and/or wounding. Tissues injured throughout the recruitment of inflammatory cells such as macrophages and neutrophils, generate a great ...

Epidermal growth factor receptor (EGFR) activation is a major cause of metastasis in many cancers, such as head and neck squamous cell carcinoma (HNSCC). However, whether the induction of cyclooxygenase-2 (COX-2) mediates EGF-enhanced HNSCC metastasis remains unclear. Interestingly, we found that EGF induced COX-2 expression mainly in HNSCC. The tumor cell transformation induced by EGF was repr...

Corresponding Author: Yenny Sylvia School of Computer Science, Bina Nusantara University, Jakarta, Indonesia Email: [email protected] Abstract: In the field of research, there are a variety of statistical methods used. Hypothesis testing is one test that is often used to obtain the conclusions of the research conducted. One hypothesis testing that is often used is the testing of hypotheses ...