Rapid growth in a number of vehicles on roadways accelerates pavement deterioration trends. Pavement inefficiency in carrying the applied load from passing vehicles results in spending significant costs on continues Maintenance and Rehabilitation (M&R) treatments. Lane closure owing to the implementation of M&R operations incurs enormous costs on road users. The research aimed to calculate, and...

This research has concentrated on the physical and socio-economic impacts of vegetation-based management scenarios targeting on flooding and soil erosion issues in the Ramian watersheds. The Ramian watershed with an approximate area of 24000 ha is located in Golestan, Iran. For each sub-watershed, four biological actions (activities) and 16 management scenarios have been considered. Physical im...

This paper presents a method concerning the integration of the benefit/cost analysis and the real genetic algorithm with various elements of reservoir dam design. The version 4.0 of HEC-RAS software and Hydro-Rout models have been used to simulate the region and flood routing in the reservoir of the dam, respectively. A mathematical programming has been prepared in MATLAB software and linked wi...

AIMS While strong correlations exist between medication adherence and health economic outcomes in type 2 diabetes, current economic analyses do not adequately consider them. We propose a new approach to incorporate adherence in cost-effectiveness analysis. METHODS We describe a theoretical approach to incorporating the effect of adherence when estimating the long-term costs and effectiveness ...

Respiratory syncytial virus infection is an important cause of morbidity. Although palivizumab prophylaxis is widely used, it is uncertain whether the cost is justified. A systematic review was therefore performed of the safety, efficacy, and the likely cost effectiveness of prophylaxis for preterm infants in the United Kingdom using a standard search strategy. The only randomised controlled tr...