BACKGROUND Corpora amylacea (CAm) are a hallmark of aging and neurodegeneration. The presence of kynurenine aminotransferases I and II (KAT I and II) in CAm in the human retina and optic nerve has been already shown. The present study aimed to examine kynurenine aminotransferase III (KAT III) immunoreactivity in CAm in the human retina and optic nerve. MATERIAL AND METHODS Polyclonal antibody...

Glycogen is a branched polymer of glucose and the carbohydrate energy store for animal cells. In the brain, it is essentially found in glial cells, although it is also present in minute amounts in neurons. In humans, loss-of-function mutations in laforin and malin, proteins involved in suppressing glycogen synthesis, induce the presence of high numbers of insoluble polyglucosan bodies in neuron...

the present study aimed to analyze reprint request e-mail messages written by postgraduates (ma students) of two fields of study, namely physics and efl, to realize the differences and similarities between the two email types. to investigate the purpose of the study, a sample of 100 e-mail messages, 50 physics and 50 efl, were analyzed according to swales’ (1990) model for reprint requests and ...

BACKGROUND The conversion of soluble peptides and proteins into polymeric amyloid structures is a hallmark of many age-related degenerative disorders, including Alzheimer's disease, type II diabetes and a variety of systemic amyloidoses. We report here that amyloid formation is linked to another major age-related phenomenon--prostate tissue remodelling in middle-aged and elderly men. METHODOL...

persian natural language processing (nlp) researchers have many limitations to access linguistic tools which are suitable for text processing. therefore, researchin persian text processing is very limited. since dataset is an important requirement for experiments and their evaluation, we aimed to create appropriate corpora for information retrieval and natural language processing in persian. th...