PURPOSE To develop a dry eye model of mouse induced by topical administration of benzalkonium chloride (BAC) and investigate the possible mechanisms. METHODS BAC at concentration of 0.2% was applied to the mouse ocular surface for 7 days. Phenol red thread tear test, tear break-up time (BUT) test, corneal inflammatory index scoring, fluorescein and rose bengal test were performed to evaluate ...

PURPOSE To evaluate the effects of hemodialysis (HD) on corneal and anterior chamber morphometry, as well as intraocular pressure (IOP) in patients with end-stage renal disease. METHODS Fifty right eyes were examined 30 minutes before and after HD. IOP was measured with a Goldmann applanation tonometer, and Ehlers' formula was used to calculate the corrected IOP values. The central corneal th...

Purpose. To compare the corneal biomechanical properties of keratoconic patients and age-matched controls using corneal visualization Scheimpflug technology (Corvis ST). Methods. Sixty keratoconic eyes from 47 keratoconus patients and 60 normal eyes from 60 controls were enrolled in this prospective study. Tomography and biomechanical parameters of all eyes were obtained with the Pentacam and C...

Purpose: To correlate corneal endothelium cell density with dry eye disease compared to an age-matched control group. Materials and Methods: In this cross-sectional study, a total of 150 eyes of 75 female students aged 19-25 years who did not have any history of eye injuries or eye disease affecting the corneal endothelium cell density, were recruited from KSU Female Campus. They were divided i...

purpose: to evaluate the correlation between corneal power and corneal horizontal white to white diameter in myopic patients scheduled for lasik surgery. methods: overall, in 840 eyes of 420 myopic subjects scheduled for lasik, horizontal white to white diameter and mean corneal power were obtained using orbscan ii. pearson correlation test and regression analysis were used to detect any correl...

purpose : to evaluate the effects of topical sesame oil in the treatment of severe corneal alkali injury in rabbits methods : in a double-blind experiment, 30 healthy white rabbits were randomized into a sesame oil treatment group (n=15) and a control group (n=15). under general anesthesia, severe corneal alkali injuries were induced by application of 1 n sodium hydroxide for 40 seconds to the ...

purpose: to present two patients with acute corneal hydrops, superimposed with infectious keratitis using topical steroids. patients and findings: the first case was a 44-year-old man with acute corneal hydrops in his left eye which was on topical steroids for one week. visual acuity was hand motion at presentation and there was a large epithelial defect with stromal infiltration and corneal ed...

Background: To investigate the relationship between high-order aberration (HOA) changes and RCST/CT (residual corneal stroma thickness/corneal thickness) after femtosecond LASIK surgery.